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Spinal Cord Interface Clinical Trials

12 actively recruiting studies

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
NCT07357428 · Phase: NA · Started 2026-03-31

The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI). The Connexus BCI is intended to be used as: (1) an ...

Sacramento, California, United States · Boston, Massachusetts, United States · Ann Arbor, Michigan, United States
Recruiting
Sensory Motor Transformations in Human Cortex
NCT01964261 · Phase: NA · Started 2013-11-01

This research study is being conducted to develop a brain controlled medical device, called a brain-machine interface. The device will provide people with a spinal cord injury some ability to control ...

Downey, California, United States · Los Angeles, California, United States · Pasadena, California, United States
Recruiting
Assessment of Neural Signals for the Control of Assistive Devices
NCT06533969 · Phase: NA · Started 2024-09-06

The study will investigate the use of motor intention-based cortical signals to trigger epidural spinal cord stimulation (ESCS) with individuals with SCI. Motor intention of UL tasks will be decoded u...

Miami, Florida, United States · Miami, Florida, United States
Recruiting
Visuomotor Prosthetic for Paralysis
NCT01958086 · Phase: NA · Started 2013-10-01

The investigators objective is to run human clinical trials in which brain activity recorded through a "brain-chip" implanted in the human brain can be used to provide novel communication capabilities...

Los Angeles, California, United States · Pasadena, California, United States · Pomona, California, United States
Recruiting
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
NCT06094205 · Phase: NA · Started 2023-10-16

The goal of this study is to improve our understanding of speech production, and to translate this into medical devices called intracortical brain-computer interfaces (iBCIs) that will enable people w...

Sacramento, California, United States
Recruiting
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)
NCT06511934 · Phase: NA · Started 2024-07-22

People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert. In ...

Boston, Massachusetts, United States
Recruiting
Cortical Recording and Stimulating Array Brain-Machine Interface
NCT01894802 · Phase: NA · Started 2013-12-01

The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of br...

Chicago, Illinois, United States · Pittsburgh, Pennsylvania, United States
Recruiting
Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)
NCT07521930 · Phase: NA · Started 2026-06

The goal of this clinical trial is to evaluate the safety and preliminary efficacy of an implantable device that records and stimulates different areas of the brain to allow adults affected by disabli...

Baltimore, Maryland, United States
Recruiting
BCI-Assisted SCS-EXS for Gait Optimization
NCT06939660 · Phase: NA · Started 2025-04-23

The goal of this clinical trial is to evaluate the safety and technical feasibility of a novel brain-machine interface (BCI)-assisted spinal cord stimulation (SCS) and exoskeleton (EXS) system in pati...

Beijing, Beijing Municipality, China
Recruiting
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
NCT00912041 · Phase: NA · Started 2009-05

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and...

Sacramento, California, United States · Stanford, California, United States · Atlanta, Georgia, United States
Recruiting
ECoG BMI for Motor and Speech Control
NCT03698149 · Phase: NA · Started 2018-11-09

Test the feasibility of using electrocorticography (ECoG) signals to control complex devices for motor and speech control in adults severely affected by neurological disorders....

San Francisco, California, United States
Recruiting
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
NCT05724173 · Phase: NA · Started 2023-10-18

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and...

Stanford, California, United States · Boston, Massachusetts, United States
Recruiting