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Stroke Rehabilitation BCI Clinical Trials

326 actively recruiting studies

Brain-computer Interface With Plantar Pneumoorthoses for Post-stroke Rehabilitation
NCT07081308 · Phase: NA · Started 2024-10-05

STUDY PURPOSE The investigators are testing a new rehabilitation system that helps stroke patients recover their ability to walk and think more clearly. This system, called brain-computer interface wi...

Moscow, Russia
Recruiting
Investigation on the Cortical Communication (CortiCom) System
NCT03567213 · Phase: NA · Started 2021-12-14

The CortiCom system consists of 510(k)-cleared components: platinum PMT subdural cortical electrode grids, a Blackrock Microsystems patient pedestal, and an external NeuroPort Neural Signal Processor....

Baltimore, Maryland, United States
Recruiting
Research on the Effectiveness of Neurorehabilitation After Stroke
NCT06753006 · Phase: NA · Started 2024-08-27

This clinical trial aims to investigate the effectiveness of a novel neurorehabilitation technology for treating stroke in adults. The study will evaluate a simulator that combines robotic orthosis, a...

Samara, Samara Oblast, Russia
Recruiting
Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation
NCT07610850 · Phase: NA · Started 2026-09-01

The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with cervical and lumbar targeted epidural electrical st...

Lausanne, Canton of Vaud, Switzerland
Recruiting
Brain Computer Interface (BCI) Integrated Wearable Hand Robotic Glove System for Upper Limb Stroke Rehabilitation
NCT06076928 · Phase: NA · Started 2024-08-01

Upper extremity (UE) recovery remains a huge rehabilitation challenge with largely incomplete recovery of the upper limb post stroke. This is due to heavier priorities placed on other stroke competenc...

Singapore, Singapore, Singapore
Recruiting
Using Upper Limb Rehabilitation Robot in Stroke Patient Rehabilitation
NCT06113380 · Phase: NA · Started 2023-10-25

A robot arm for upper limb rehabilitation is intended to achieve rehabilitation effects through the study of robot control theory and the integration of sensors such as sEMG. The goal is to reduce the...

Taipei, Taiwan
Recruiting
BCI-FES for Upper Limb Rehabilitation in Chronic Stroke
NCT06409754 · Phase: NA · Started 2024-08-06

The objective of this research is to evaluate the efficacy of an experimental therapy for motor recovery of the arm after a stroke, which includes the application of a functional electrical stimulatio...

Mexico City, Mexico City, Mexico
Recruiting
fNIRS-BCI Neurofeedback in Stroke Rehabilitation
NCT06503484 · Phase: NA · Started 2024-12-12

Objectives: 1) To compare the effects of closed-loop brain-computer interface (BCI) driven observational imitation training versus sham BCI open-loop observational imitation training on improving uppe...

Hong Kong, Hong Kong, Hong Kong
Recruiting
Magnetic Brain Stimulation and Computer-based Motor Training for Rehabilitation After Stroke
NCT06116942 · Phase: NA · Started 2023-11-08

The goal of the present clinical trial is to explore whether an innovative technology-based approach can help individuals who have had a stroke and can no longer move their hands with ease. Our approa...

Leipzig, Saxony, Germany
Recruiting
BCI With Virtual Reality for Stroke Rehabilitation: A Crossover Study
NCT07374276 · Phase: NA · Started 2026-01-05

The goal of this clinical trial is to investigate if training sessions of motor imagery associated with brain-computer interface and motor observation through virtual reality (MI-VR-BCI) can help to i...

Alcabideche, Lisbon District, Portugal
Recruiting
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
NCT04875936 · Phase: NA · Started 2023-04-03

The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel bra...

West Orange, New Jersey, United States
Recruiting
Neurofeedback-EEG Rehabilitation Protocol on Motor Recovery in the Subacute Phase Post-stroke (CUSTOM-NF-STROKE)
NCT06212219 · Phase: NA · Started 2024-01-08

Neurofeedback (NF) is a procedure for providing direct sensory feedback (in the form of visual, auditory or tactile stimulation) to a patient about their brain activity when performing a cognitive or ...

Toulouse, France
Recruiting
fNIRS Neurofeedback for Post-stroke Hand Rehabilitation
NCT07262528 · Phase: NA · Started 2025-12-01

Cardiovascular diseases are one of the main causes of disability. Among post-stroke individuals, 80% experience upper limb dysfunction, while only 5% to 20% of individuals regain full limb and hand fu...

Rzeszów, Poland
Recruiting
earlY Upper Limb Rehabilitation WIth EEG-Neurofeedback After Stroke
NCT05884762 · Phase: NA · Started 2024-02-20

The aim of this study is to evaluate the effect of early rehabilitation treatment by electroencephalographic neurofeedback on upper limb motor function after stroke. Researchers will compare : Inter...

Rennes, France
Recruiting
Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors
NCT07266662 · Phase: NA · Started 2025-11-25

This study aims to evaluate the effectiveness of two rehabilitation techniques-Sensory Augmentation (using mirror therapy) and Neuromodulation (using transcranial direct current stimulation, tDCS)-in ...

Lahore, Punjab Province, Pakistan · Lahore, Punjab Province, Pakistan
Recruiting
Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
NCT07050355 · Phase: NA · Started 2024-11-01

Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-d...

Durham, North Carolina, United States · Charleston, South Carolina, United States
Recruiting
A Trial of Rehabilitation Paired with VNS for Motor Function in Patients with Stroke (Repair Study)
NCT06722677 · Phase: NA · Started 2024-11-19

The goal of this clinical trial is to investigate the efficacy and safety of vagus nerve stimulation (VNS) paired with rehabilitation for enhancing upper extremity motor function after ischemic stroke...

Hefei, Anhui, China · Beijing, Beijing Municipality, China · Beijing, Beijing Municipality, China
Recruiting
Research on Binaural Synchronous Vagus Nerve Regulation of Sensorimotor Disorders After Cerebral Infarction
NCT07081568 · Phase: NA · Started 2025-06-25

The aim of this study is to determine the efficacy and safety of binaural synchronous vagus nerve regulation in the treatment of patients with sensory and motor dysfunction after cerebral infarction t...

Nanchang, Jiangxi, China
Recruiting
Repetitive Transcranial Magnetic Stimulation Combined With Bimanual Therapy for Upper Limb Stroke Rehabilitation
NCT07054424 · Phase: NA · Started 2025-06-05

The goal of this clinical trial is to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with machine-assisted bimanual therapy (BT) can improve upper limb function in stro...

Taoyuan, Taiwan
Recruiting
Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post
NCT05584124 · Phase: PHASE2 · Started 2023-04-10

This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enro...

Decatur, Georgia, United States
Recruiting
Non-invasive Neuromodulation NESA Application in the Rehabilitation of Stroke Sequelae
NCT05853952 · Phase: NA · Started 2023-04-24

To evaluate whether NESA microcurrents can be used as an effective treatment for various sequelae present in stroke patients, specifically in the treatment of spasticity, balance, pain; and whether it...

Las Palmas de Gran Canaria, Las Palmas, Spain
Recruiting
Non-invasive VNS in Stroke Recovery
NCT06761404 · Phase: NA · Started 2025-04-15

To evaluate feasibility and effectiveness of non-invasive VNS to enhance stroke recovery...

Houston, Texas, United States
Recruiting
Transcranial Magnetic Stimulation Synchronized with Motor Task Training for Post-Stroke Rehabilitation
NCT06849505 · Phase: NA · Started 2024-07-02

The goal of this clinical trials is to investigate the effectiveness of individualized online repetitive transcranial magnetic stimulation (rTMS) in enhancing upper limb motor rehabilitation during th...

Shanghai, Shanghai Municipality, China
Recruiting
Effects of Trans-Auricular Vagal Stimulation on Neuromotor Recovery in Subacute Stroke During Technological and Traditio
NCT07254390 · Phase: NA · Started 2025-01-08

This randomized pilot clinical study aims to investigate the effects of trans-auricular vagus nerve stimulation (tVNS) on neuromotor recovery in patients in the subacute phase after stroke. Participan...

Montescano, Pavia, Italy
Recruiting
Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke
NCT07113041 · Phase: NA · Started 2025-06-01

Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effectiveness of a combined intervention involving robotic balance training and noninvasive brain stimulation in improving balance func...

West Orange, New Jersey, United States
Recruiting
Neurophysiological and Behavioral Study of the Cognitive Deficits Associated With Cerebral Small Vessel Disease in the S
NCT07068620 · Phase: NA · Started 2025-08-07

Cerebral small vessel disease (cSVD) is characterized by an alteration of the structure and function of small penetrating brain arteries. Highly prevalent in older individuals from the general populat...

Bordeaux, France
Recruiting
Functional and Quality of Life Effects of the Mollii Neuromodulatory Suit in Patients With Stroke and Multiple Sclerosis
NCT07333222 · Phase: NA · Started 2026-01-12

* Objective assessment of clinical symptoms resulting from stroke, as well as changes in mobility and quality of life, and determination of changes resulting from therapies * Objective assessment of t...

Kaposvár, Somogy County, Hungary
Recruiting
Effect of Immersive Virtual Reality With Multisensory Stimulation on the Functional Impact of Hemineglect Secondary to a
NCT06719063 · Phase: NA · Started 2025-04-04

A stroke is a common and potentially serious condition that affects 130,000 people each year in France. It is the second leading cause of major cognitive disorders after Alzheimer's disease. Heminegl...

Saint-Sébastien-de-Morsent, France
Recruiting
Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With
NCT06838013 · Phase: NA · Started 2024-06-17

This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task...

Hong Kong, Hong Kong
Recruiting
Hybrid Robot+FES Stroke Rehabilitation
NCT04550728 · Phase: PHASE1, PHASE2 · Started 2021-08-01

The investigators have developed a novel robot-guided stretching under intelligent control and combine it with active movement training, which helped increase joint ROM, reduce spasticity and joint st...

Baltimore, Maryland, United States
Recruiting
Comparison of Four-Channel Functional Electrical Stimulation vs. One-Channel Electrical Stimulation on Moderate Arm/Hand
NCT07098572 · Phase: NA · Started 2025-07-14

This study will compare two treatments that may help participants recover after having suffered from stroke. Persons who experience weakness or paralysis of their arms/hands will be randomly placed in...

Hermagor, Carinthia, Austria · Zirl, Tyrol, Austria · Linz, Upper Austria, Austria
Recruiting
Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study.
NCT07130929 · Phase: NA · Started 2025-09-23

This study aims to evaluate the effectiveness of physiotherapy treatment combined with functional electrical stimulation (FES) in a small group of patients with severe acquired brain injury (SABI) of ...

Florence, FI, Italy
Recruiting
Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke Aphasia
NCT05303649 · Phase: NA · Started 2022-09-02

Aphasia is an impairment in the ability to express and/or understand language, commonly observed after stroke to the language dominant (left) hemisphere. Despite natural tendency to spontaneous functi...

Warsaw, Masovian Voivodeship, Poland
Recruiting
Impact of VNS With Rehab on Gait Post-Stroke
NCT07643337 · Phase: NA · Started 2026-06

This is a prospective, double-blinded, randomized controlled study to evaluate the impact of Vagus Nerve Stimulation (VNS) therapy on lower limb function....

Buffalo, New York, United States
Recruiting
At-Home taVNS - Stroke Rehab
NCT06616831 · Phase: NA · Started 2024-10-28

Early evidence suggests the benefits of post-stroke motor rehabilitation may be enhanced by applying electrical stimulation to the ear. This study aims to test the new approach of pairing ear stimulat...

Charleston, South Carolina, United States
Recruiting
Associative Peripheral Stimulation for Reduction of Motor Impairment During Acute Period of Stroke Recovery
NCT06575140 · Phase: NA · Started 2021-12-18

Associative Peripheral Stimulation (APS) is a non-invasive therapy intended for stroke rehabilitation involving transcutaneous electrical muscle stimulation paired with voluntary movement. This pilot ...

Mexico City, Mexico · Mexico City, Mexico · Mexico City, Mexico
Recruiting
Pilot/Pivotal Study of DBS+Rehab After Stroke
NCT05701280 · Phase: NA · Started 2023-02-03

The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke....

Phoenix, Arizona, United States · Jacksonville, Florida, United States · Baltimore, Maryland, United States
Recruiting
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
NCT03870672 · Phase: NA · Started 2019-05-14

This study is a necessary and important step in the development of a new therapy for upper limb functional recovery in patients with severe motor impairment. It is the first clinical trial of non-inva...

Cleveland, Ohio, United States
Recruiting
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
NCT05866003 · Phase: NA · Started 2023-07-01

After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a pe...

Cleveland, Ohio, United States
Recruiting
Efficacy of Cerebello-spinal Direct Current Stimulation (csDCS) on Functional Mobility in Chronic Stroke Patients
NCT07073287 · Phase: PHASE2 · Started 2024-05-01

The aim of this clinical trial is to determine if cerebello-spinal direct current stimulation (csDCS) is effective in treating gait disorders in individuals with chronic stroke. Additionally, the tria...

João Pessoa, Paraíba, Brazil · Recife, Pernambuco, Brazil · Rio de Janeiro, Rio de Janeiro, Brazil
Recruiting
Study on the Effects of an EMG-controlled Functional Electrical Stimulator for Upper Limb for Post-stroke Patients
NCT06928857 · Phase: NA · Started 2025-03-03

Upper limb disabilities are among the most debilitating issues after a cerebral stroke. One promising approach in motor rehabilitation is the use of functional electrical stimulation (FES). This techn...

Genova, Italy · La Spezia, Italy · Milan, Italy
Recruiting
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
NCT04897334 · Phase: NA · Started 2021-09-21

The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve c...

Philadelphia, Pennsylvania, United States
Recruiting
Brain Stimulation Combined With Watching Hand Movements to Improve Hand Recovery in Chronic Stroke
NCT07400939 · Phase: NA · Started 2026-04-01

This study investigates the neurophysiological mechanisms underlying the combined use of transcranial direct current stimulation (tDCS) and action observation therapy (AOT) for hand motor recovery in ...

Kota Kinabalu, Sabah, Malaysia · Kota Kinabalu, Sabah, Malaysia
Recruiting
Patient-tailored Transcranial Direct Current Stimulation to Improve Stroke Rehabilitation
NCT05355831 · Phase: NA · Started 2022-08-28

In a double-blinded sham-controlled study the effect of patient-tailored transcranial direct current stimulation during rehabilitation training will be examined....

Copenhagen, Denmark · Herlev, Denmark · Hvidovre, Denmark
Recruiting
RESPARK - Brain Q for Chronic Stroke
NCT07095920 · Phase: NA · Started 2025-08-27

This trial tests a promising new intervention to promote post-stroke neural reorganization and functional recovery. The Q Therapeutic (BQ 3.0) is a wearable medical system that produces and delivers n...

Jacksonville, Florida, United States
Recruiting
Comparison of the Effects of Mirror Therapy,rTMS and Robotic-assisted Hand Therapy in Stroke Patients
NCT06750692 · Phase: NA · Started 2024-12-27

The aim of the study is to investigate the comparison of the effects of mirror therapy, Repetitive Transcranial Magnetic Stimulation and robot-assisted hand therapy added to conventional neurological ...

Afyonkarahisar, Turkey (Türkiye)
Recruiting
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
NCT07631078 · Phase: NA · Started 2026-07-01

kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who...

Berkeley, California, United States
Recruiting
Comparative Effects of Functional Electrical Stimulation and Mirror Therapy for Foot Clearance Among Patients With Sub-a
NCT07448532 · Phase: NA · Started 2026-01-22

This study aims to evaluate the effectiveness of two rehabilitation techniques- Functional Electrical Stimulation (FES) and Mirror Therapy (MT)-in improving motor recovery among stroke survivors. Stro...

Lahore, Punjab Province, Pakistan · Lahore, Punjab Province, Pakistan
Recruiting
Repetitive Transcranial Magnetic Stimulation in Cardiac Autonomic Dysfunction
NCT07482501 · Phase: NA · Started 2026-03-26

The aim of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) added to conventional neurological rehabilitation on heart rate variability (HRV), quality of...

Afyonkarahisar, Turkey (Türkiye)
Recruiting
Cerebellar Stimulation for Aphasia Rehabilitation
NCT05093673 · Phase: NA · Started 2021-10-25

The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS...

Baltimore, Maryland, United States
Recruiting
FES-Assisted Upper Extremity Ergometer Training in Subacute Stroke
NCT07484854 · Phase: NA · Started 2024-12-09

Stroke is a leading cause of long-term disability and often results in impaired upper extremity function and reduced aerobic capacity. Improving both cardiovascular and function is an important goal i...

Ankara, Çankaya, Turkey (Türkiye)
Recruiting
Improving Measurement and Treatment of Post-stroke Neglect
NCT03317860 · Phase: NA · Started 2018-07-02

This study examines how to best assess and treat post-stroke neglect. This study will examine the preliminary effects of an innovative intervention (repetitive task-specific practice + transcranial di...

Pittsburgh, Pennsylvania, United States
Recruiting
Using AI Systems to Optimize the Clinical Outcome of Stroke Patients
NCT06828679 · Phase: NA · Started 2025-07-01

This project addresses the imminent challenge of providing adequate motor rehabilitation to a growing number of stroke survivors amidst the ageing population, decreasing age of stroke, and shortage of...

Hong Kong, Sha Tin, Hong Kong
Recruiting
Transcutaneous Auricular Vagus Nerve Stimulation for Treating Post-stroke Dysphagia
NCT06827301 · Phase: NA · Started 2024-11-23

The aim of the present project is to use transcutaneous auricular vagus nerve stimulation (t-VNS) for the treatment of dysphagia in acute stroke patients to improve swallowing function and reduce mort...

Roma, RM, Italy
Recruiting
Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Moto
NCT07236216 · Phase: NA · Started 2025-12-20

The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conv...

Nakhon Pathom, Thailand
Recruiting
The RETRAIN Trial Phase 2
NCT07197996 · Phase: NA · Started 2025-07-01

Ischaemic strokes, caused by a disruption in the brain's blood supply, are the second leading cause of death and disability in the United Kingdom. This single-center prospective randomised study aims ...

Chester, Cheshire, United Kingdom
Recruiting
Novel Non-invasive Brain Stimulation Techniques in Neurological Rehabilitation
NCT05766059 · Phase: NA · Started 2023-02-08

Paired associative stimulation (PAS) is a non-invasive brain stimulation protocol, where two stimuli (a peripheral and a cortical one, the latter delivered with transcranial magnetic stimulation - TMS...

Milan, Lombardy, Italy
Recruiting
Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation
NCT03857529 · Phase: NA · Started 2019-08-01

This pilot study for stroke patients with chronic upper limb hemiplegia will examine the effects of non-invasive brain stimulation and neuromuscular electrical stimulation on hand motor control and co...

Cleveland, Ohio, United States
Recruiting
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
NCT04755699 · Phase: EARLY_PHASE1 · Started 2020-12-02

This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimu...

Manhasset, New York, United States
Recruiting
Wether VNS in Early Stage (3 Months) is Safe and More Beneficial for Post-stroke Motor Rehabilitation
NCT06938243 · Phase: PHASE1 · Started 2025-05-01

Upper-extremity impairment after stroke remains a major therapeutic challenge and a target of neuromodulation treatment efforts. In previous study, Vagus nerve stimulation was constricted to patients ...

Jinan, Shandong, China
Recruiting
High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
NCT06409143 · Phase: NA · Started 2024-08-15

Upper limb hemiparesis is the most common sequelae in patients, severely impacting their independence and quality of life. Transcranial electrical stimulation (tCES) is a non-invasive and safe treatme...

New Taipei City, Taiwan · Taipei, Taiwan · Taipei, Taiwan
Recruiting
Effect of Visual Biofeedback-Assisted Oropharyngeal Exercises in Post-Stroke Dysphagia
NCT07492719 · Phase: NA · Started 2026-02-16

Post-stroke dysphagia is a common complication that negatively affects nutritional status, quality of life, and morbidity. Conventional swallowing rehabilitation, including oropharyngeal exercises and...

Ankara, Turkey (Türkiye)
Recruiting
The Potential of Robotic-Assisted Gait Training in a Rehabilitation Setting
NCT07529054 · Phase: NA · Started 2026-01-05

Robotic-assisted gait training (RAGT) devices, such as the Lokomat®, are commonly used to support gait rehabilitation by enabling repetitive, task-specific walking movements. The functional propriocep...

Gröbming, Styria, Austria
Recruiting
Visuo-Vestibular VR-based Stimulation Effects on Balance and Gait in Stroke Survivors
NCT06780488 · Phase: NA · Started 2025-01-01

This pilot study aims to evaluate the effect of a specfic Virtual-Reality-Based rehabilitation training in patients with stroke. A total of 38 patients with stroke (more than 6 months from the acute e...

Roma, RM, Italy
Recruiting
Mirror Therapy with Cutaneous Electrical Sensory Stimulation on Lower Limb Motor Functions in Stroke
NCT03622879 · Phase: NA · Started 2018-07-02

This study aims to evaluate the effectiveness of concurrent mirror therapy (MT) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented traini...

Hong Kong, Hong Kong
Recruiting
Cerebellar Deep Brain Stimulation or VNS for Chronic Post-stroke Motor Rehabilitation
NCT06303960 · Phase: EARLY_PHASE1 · Started 2024-03-15

Upper-extremity impairment after stroke remains a major therapeutic challenge and a target of neuromodulation treatment efforts.In this open-label, randomized phase I trial, we applied deep brain stim...

Jinan, Shandong, China
Recruiting
EMG Control Assistance Virtual Reality Interface Coupled With Cerebellar-iTBS for Arm Recovery After Stroke (ERICA)
NCT06911671 · Phase: NA · Started 2025-04-01

The investigators hypothesize that a myoelectric (EMG) controlled virtual reality (VR) interface allows for effective upper limb motor recovery of stroke patients. EMG control offers the possibility t...

Roma, Rome, Italy
Recruiting
Stimulating Postural Control to Augment Rehabilitation After Cerebral Stroke (SPARC): a Pilot Trial
NCT06987682 · Phase: NA · Started 2025-05-21

People living with stroke have a high risk of falling and this risk increases as mobility improves over the first year post-stroke. Despite the high number of falls, there is a lack of interventions t...

Toronto, Ontario, Canada
Recruiting
Deep Anterior Cerebellar Stimulation in Treatment of Poststroke Spasticity and Motor Function Impairment.
NCT07190092 · Phase: NA · Started 2024-09-01

The aim of this clinical trial is to determine whether deep brain stimulation (DBS) interventions improve rehabilitation and functional recovery in patients with post-stroke spasticity who meet the ot...

Bydgoszcz, Poland
Recruiting
Virtual Reality and Neurostimulation for Early Stroke Rehabilitation
NCT06887231 · Phase: NA · Started 2025-03-17

Stroke is one of the leading causes of disability, leaving millions of individuals each year impaired with lasting motor and sensory impairments. In the subacute phase, which goes from the first week ...

Vienna, State of Vienna, Austria
Recruiting
Efficacy of Rehabilitation Using Action Observation and Muscle Stimulation in Post-stroke Patients.
NCT06055569 · Phase: NA · Started 2023-11-01

Stroke is the third most common cause of disability worldwide and leads to upper limb motor disease in more than half of people affected. Recent data demonstrate that upper limb rehabilitation can be...

Milan, Italia, Italy
Recruiting
Effectiveness of Active Exploration of Simulated Textures for Sensorimotor Recovery
NCT06962397 · Phase: NA · Started 2024-10-08

Parallel-group, single-blinded controlled clinical trial. The study includes people aged 18-80 years, more than one month after stroke, with confirmed diagnosis, MoCA ≥ 20, and Barthel Index ≥ 3. The...

Moscow, Russia
Recruiting
Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation
NCT06842095 · Phase: NA · Started 2025-02-01

Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) ...

Oxford, United Kingdom
Recruiting
Individualized Neuro-Modulation Paired With Cerebellar Therapy
NCT07642856 · Phase: NA · Started 2026-06-30

The purpose of this project is to evaluate feasibility and preliminary efficacy of pairing personalized transcranial direct current stimulation (tDCS) with individualized rehabilitation therapy in peo...

Baltimore, Maryland, United States
Recruiting
Electroacupuncture and rTMS for Post-Stroke Motor Recovery
NCT07113990 · Phase: NA · Started 2025-08-27

This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS ...

Fuzhou, Fujian, China · Fuzhou, Fujian, China · Wenzhou, Zhejiang, China
Recruiting
Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke
NCT05591196 · Phase: NA · Started 2022-10-01

The recovery from a stroke is often incomplete. It is the leading cause of acquired permanent disability in the adult population. Persistent functional loss of the hand and arm contributes significant...

Seattle, Washington, United States
Recruiting
Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Trials in Canada
NCT06576089 · Phase: NA · Started 2025-06-16

Stroke is a major health issue in Canada. Stroke affects over 400,000 Canadians, and this number is expected to nearly double by 2038. Research studies in stroke recovery can help us better understand...

Calgary, Alberta, Canada · Vancouver, British Columbia, Canada · Halifax, Nova Scotia, Canada
Recruiting
Mobile Cognitive Behavioral Therapy for Stroke
NCT06689878 · Phase: NA · Started 2025-02-25

This study aims to assess the feasibility and acceptability of "MAYA", a mobile cognitive behavioral therapy app for anxiety and mood disorders, in adults who have had a stroke....

New York, New York, United States
Recruiting
Effects of Virtual Reality Multisensory Cooperative Task-Oriented Mirror Therapy
NCT07139379 · Phase: NA · Started 2025-06-24

In the proposed study, the investigators assumed that Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Therapy (VRMCTOMT) will provide a better treatment effects than traditional vi...

Tainan, Taiwan, Taiwan
Recruiting
Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients
NCT06802159 · Phase: NA · Started 2025-01-09

Stroke remains one of the leading causes of mortality and disability worldwide. Between 30% and 40% of patients who have had an acute cerebral hemorrhage, develop unilateral spatial neglect syndrome (...

Moscow, Moscow, Russia · Moscow, Russia
Recruiting
Feasibility Study of Caregiver-Assist Strategy Training
NCT06741475 · Phase: NA · Started 2025-02-04

The goal of this study is to examine the feasibility of delivering an innovative intervention, caregiver-assisted strategy training (CaST), targeting enhancing activity functions in community-dwelling...

New Taipei City, Taiwan · Taipei, Taiwan · Taipei, Taiwan
Recruiting
Robot-Assisted Tai Chi for Upper Limb Rehabilitation in Stroke Patients
NCT06897631 · Phase: NA · Started 2025-04-29

This study aims to compare the effectiveness of Robot-Assisted Tai Chi Training (RATT) versus conventional rehabilitation in improving upper limb motor function post-stroke, and to explore the neuromu...

Fuzhou, Fujian, China · Fuzhou, Fujian, China
Recruiting
Videographic Feedback and Walk Rehabilitation in Post-Cerebrovascular Accident
NCT05024981 · Phase: NA · Started 2022-03-04

Cerebrovascular Accident affects the majority of the elderly population and its frequency is constantly increasing. The resulting deficits are numerous and lead in particular to an alteration in the q...

Nice, Alpes-Maritime, France
Recruiting
The Effect of Motor Imagery on Upper Extremity Function in Stroke Rehabilitation
NCT07565363 · Phase: NA · Started 2026-05-01

Stroke is one of the leading causes of mortality and disability worldwide. A proportion of individuals who experience a stroke fail to achieve the desired level of motor recovery in the affected upper...

Istanbul, Turkey (Türkiye)
Recruiting
The Canadian Maraviroc Randomized Controlled Trial To Augment Rehabilitation Outcomes After Stroke
NCT04789616 · Phase: PHASE2 · Started 2022-09-15

The CAMAROS trial is a randomized controlled phase II trial analyzing the effect of coupling a C-C chemokine receptor 5 (CCR5) antagonist, Maraviroc (Celsentri), and exercise to improve both upper and...

Calgary, Alberta, Canada · Vancouver, British Columbia, Canada · Halifax, Nova Scotia, Canada
Recruiting
Reaching the Unreached: Home-Based Telerehabilitation for Stroke Survivors
NCT07467785 · Phase: NA · Started 2026-06-02

After a stroke, many people have trouble using their arms and hands. This can make daily tasks-like eating, dressing, or writing-very hard. In Alberta, especially in small towns and rural areas, many ...

Edmonton, Alberta, Canada
Recruiting
Virtual Reality for Post-Stroke Gait Rehabilitation
NCT07201974 · Phase: NA · Started 2026-02-01

The goal of this clinical trial is to: (1) implement and test the feasibility of a new VR-ODT intervention offered as part of usual therapy time of patients with a sub-acute stoke; (2) explore the acc...

Laval, Quebec, Canada
Recruiting
Exergame and Robotic Therapy Impact on Tenascin-C and Functional Outcome on Stroke Patients
NCT06563206 · Phase: NA · Started 2023-10-01

This clinical trial aims to compare the effectiveness of Robotic versus Exergame versus Standard therapy to improve hand function among post-stroke patients. The main questions it aims to answer are: ...

Makassar, South Sulawesi, Indonesia · Makassar, South Sulawesi, Indonesia
Recruiting
Implementation of a Registry for Patients With Stroke
NCT05389878 · Phase: Not specified · Started 2022-01-12

Pathology registers are scientific research tools for the development of epidemiological and clinical studies and health planning, which allows access to useful elements for planning adequate health s...

Florence, Italy · Milan, Italy · Parma, Italy
Recruiting
Focused Intensive Repeated Stepping During Inpatient Rehabilitation Poststroke - A Quality Improvement Project
NCT05393661 · Phase: Not specified · Started 2017-01-01

The purpose of this quality improvement project was first to monitor usual physical therapy care (types \& cardiovascular intensity of interventions and amount of stepping practice provided) and outco...

Indianapolis, Indiana, United States
Recruiting
Effects of CTAR and a Swallowing Pressure Ball in Older Stroke Adults
NCT07620210 · Phase: NA · Started 2026-03-18

This study aims to investigate the effectiveness of resistance swallowing rehabilitation using Chin Tuck Against Resistance (CTAR) exercises combined with an innovative swallowing pressure ball in imp...

Tainan, Tainan City, Taiwan
Recruiting
EMG-guided Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction
NCT07531264 · Phase: EARLY_PHASE1 · Started 2023-10-10

The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients ...

Houston, Texas, United States
Recruiting
Telerehabilitation Robotics for Upper Limb Rehabilitation After STroke
NCT06270459 · Phase: NA · Started 2024-11-01

There has been an observed decrease in motor and functional ability and non-use of the impaired limb in chronic patients. This is due to the immediate drop in intensive daily therapy (5 days per week ...

Singapore, Singapore, Singapore
Recruiting
Behavioral Assessment Method Index
NCT07291479 · Phase: Not specified · Started 2023-07-07

The overall goal of this study is to develop and improve assessment methods for children with and without perinatal arterial ischemic stroke (PAS)/hemiparetic cerebral palsy (HCP). The focus is on beh...

Columbus, Ohio, United States
Recruiting
Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Sub
NCT06107010 · Phase: NA · Started 2023-06-12

The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial. This clinical investigation is designed to t...

Créteil, France · Pionsat, France · Bad Aibling, Germany
Recruiting
Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors
NCT06758505 · Phase: NA · Started 2025-09-29

The goal of this clinical trial is to test a new rehabilitation program, combining acceptance and commitment therapy with strategy training (ACES), to help people resume social participation after str...

Pittsburgh, Pennsylvania, United States
Recruiting
Post-Stroke Fatigue Perception Study (ReFast)
NCT07444151 · Phase: Not specified · Started 2026-01-27

The goal of this observational study is to better understand fatigue after stroke. Many people feel ongoing tiredness months or years after a stroke. This fatigue may affect daily activities, work, an...

Carouge, Canton of Geneva, Switzerland
Recruiting
Prevention and Rehabilitation of Stroke in Uganda
NCT05807269 · Phase: Not specified · Started 2023-11-01

Stroke is increasing in low-income countries in Africa, and knowledge is lacking on risk factors and how to prevent stroke as well as how to best use the resources for rehabilitation after stroke whic...

Hoima, Uganda · Kampala, Uganda
Recruiting
Biofeedback for Hemianopia Vision Rehabilitation
NCT05397873 · Phase: NA · Started 2021-12-01

Patients with brain injury secondary to stroke, surgery, or trauma frequently suffer from homonymous hemianopia, defined as vision loss in one hemifield secondary to retro- chiasmal lesion. Classic an...

Toronto, Ontario, Canada
Recruiting
Aspirational Rehabilitation Coaching for Holistic Health (ARCH): A Pilot Pre-Post Experimental Study
NCT06596551 · Phase: NA · Started 2024-03-01

The ARCH programme is a novel, strength-based, dyadic, multicomponent psychosocial intervention that blends together psychoeducation, psychosocial support and self-compassion practices to aid first-ti...

Singapore, Singapore
Recruiting
Assessment of Eye Movements in Stroke Patients and Closed-loop Intervention
NCT06965673 · Phase: NA · Started 2023-04-01

The current study evaluates first the assumption that eye-movements during free viewing behavior are potential biomarkers of visuospatial deficits in stroke population. Second, it assesses the feasibi...

Padova, PD, Italy · Venice-Lido, VE, Italy
Recruiting
Hand Exoskeleton Training Study
NCT06786858 · Phase: NA · Started 2022-01-04

The goal of this study is to evaluate the HandMATE device's effectiveness in the rehabilitation of stroke patients and asses if the HandMATE application is received well by stroke survivors. Particip...

Washington D.C., District of Columbia, United States
Recruiting
Robot-Assisted Gait Training vs Visual Feedback Balance Training in Stroke
NCT07471919 · Phase: NA · Started 2026-03-15

Stroke frequently leads to balance impairment and gait dysfunction, increasing fall risk and limiting functional independence. Technology-assisted rehabilitation approaches such as robot-assisted gait...

Bolu, Turkey (Türkiye)
Recruiting
Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes
NCT06640101 · Phase: NA · Started 2025-02-21

This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance ...

Shenzhen, None Selected, China
Recruiting
Investigation of the Effects of Visual-Motor Based Training on Upper Extremity Functions in Individuals With Stroke
NCT07055945 · Phase: NA · Started 2025-08-28

The purpose of this study is to investigate the effects of visual-motor based training and physiotherapy program on upper extremity functions in individuals with stroke and to compare with physiothera...

Ankara, Türkiye, Turkey (Türkiye)
Recruiting
A Pilot Return-to-Work Cognitive Intervention After Stroke
NCT07116187 · Phase: NA · Started 2025-08-08

This study addresses the growing burden of stroke in Singapore and highlights the lack of rehabilitation services for return to work after stroke. Despite functional physical recovery, many stroke sur...

Singapore, Singapore
Recruiting
Effects of Appropriate Technology for Home-based Rehabilitation in Patients With Post-stroke Physical Dysfunction
NCT06437587 · Phase: NA · Started 2024-06-01

The goal of this clinical trial is to assess the effect of S-HRAT to improve patients' motor function and activities of daily living....

Daqing, Heilongjiang, China
Recruiting
Improving Sleep and Learning in Rehabilitation After Stroke, Part 2
NCT05511285 · Phase: NA · Started 2022-09-13

This study will explore whether sleep in stroke survivors is improved with digital cognitive behavioural therapy for insomnia (Sleepio), in comparison to treatment as usual, and will explore whether c...

Oxford, United Kingdom
Recruiting
Effects of Different Pressure Garments on Upper Extremity Sensorimotor Functions and Quality of Life After Stroke
NCT06587308 · Phase: NA · Started 2024-10-08

The study aims to compare the effects of dorsal-double-layered 10% circumferential reduction (DD-10), single-layered 10% circumferential reduction (S-10), and single-layered no circumferential reducti...

Weifang, Shandong, China · Weifang, Shandong, China · Weifang, Shandong, China
Recruiting
Cognitive Recovery Via Sensor-based Robotic Upper Limb Rehabilitation in Neurological Disorders
NCT07384143 · Phase: NA · Started 2025-02-11

The goal of this clinical trial is to learn if sensor-based robotic upper limb rehabilitation can improve cognitive and motor functions in adults with neurological and neurodegenerative disorders, inc...

Messina, Maine, Italy
Recruiting
Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients.
NCT05945212 · Phase: NA · Started 2024-03-12

The aim of the vibration intervention proposed in the current study is to allow a better neuromotor recovery in subacute stroke patients when compared with standard rehabilitation alone. These last ye...

Le Chambon-Feugerolles, France · Rive-de-Gier, France · Roanne, France
Recruiting
Factors and Preferences in Patient Selection of Rehabilitation Care Following Acute Stroke: A Predictive Correlational S
NCT07089095 · Phase: Not specified · Started 2023-05-11

Background and Purpose Patients with stroke have to receive the rehabilitation care after medical condition has stabilized. In recent years, the long-term care policy offers more options available for...

Taipei, Taiwan
Recruiting
Urinary Disorders in Subacute Patients After Stroke
NCT04078373 · Phase: Not specified · Started 2019-06-01

This observational study will address urinary disorders in subacute stroke patients. Patients without and with urinary disorders will be compared, and treatment outcome will be assessed among the latt...

Ljubljana, Slovenia
Recruiting
Multi-domain Improvements in High-TEchnology Rehabilitation Programs for Post-stroke Patients
NCT06489145 · Phase: NA · Started 2024-06-24

Through a multi-method, multi-informant, and patient-centred approach, the study aims to investigate the experience of use and the effectiveness of rehabilitation technology (robotics and virtual real...

Milan, Italy
Recruiting
Computerized Cognitive Rehabilitation of Executive Deficits in Stroke Patients
NCT05169632 · Phase: NA · Started 2022-03-17

WHO: 32 participants with executive deficits related to a stroke, able to engage in moderate physical activity. WHY: Around one third of stroke patients suffer from cognitive deficits in the long ter...

Lausanne, Canton of Vaud, Switzerland
Recruiting
Effect of Occupational Therapy at Home E-Rehabilitation (OTHER) for Persons Post-stroke
NCT05855226 · Phase: NA · Started 2023-03-13

The goal of this (cost)effectiveness study is to compare care as usual with OTHER-intervention in Cerebro Vascular Accident (CVA) older adults in Geriatric Rehabilitation (GR). The main question\[s\] ...

Tiel, Gelderland, Netherlands · Groesbeek, Gerlderland, Netherlands · Brunssum, Limburg, Netherlands
Recruiting
Effect of Motor Imagery With Virtual Reality in Patients With Stroke
NCT04215679 · Phase: NA · Started 2021-12-01

Virtual reality applications in hemiplegia rehabilitation are gaining popularity. It is claimed that, apart from implementing a function, imagining that function can trigger synaptic connections....

Bolu, Merkez, Turkey (Türkiye)
Recruiting
Traumatic Brain Injury and Stroke Long Term Outcome
NCT03399929 · Phase: Not specified · Started 2016-05-04

Investigators will determine the long-lasting effects of post-acute rehabilitation after traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects of rehabilitation...

Encino, California, United States
Recruiting
An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation
NCT04187131 · Phase: NA · Started 2023-06-01

The aim of this phase is to examine the feasibility and acceptability of the Augmented Reality (AR)-based and electroencephalography (EEG)-based neglect detection and rehabilitation tool....

Boston, Massachusetts, United States · Pittsburgh, Pennsylvania, United States
Recruiting
Sleep and Stroke Rehabilitation Study
NCT07579871 · Phase: Not specified · Started 2026-03-18

The study aims to map sleep disorders and their impact on the ability to engage in an active daily life among people who have had a stroke, with particular focus on how sleep apnea can be identified. ...

Lund, Skåne County, Sweden
Recruiting
Evaluation of the Efficacy of Permanent Course Combined Therapy With CYTOFLAVIN® Intravenous Solution and CYTOFLAVIN Tab
NCT06735898 · Phase: Not specified · Started 2024-03-01

Post intensive care syndrome (PIC syndrome) is an important problem in modern intensive care strategy. Understanding the mechanisms of PIC syndrome helps prevent it in patients with respiratory, neuro...

Yekaterinburg, Sverdlovsk Oblast, Russia
Recruiting
Feasibility and Cost of Robot-assisted Upper Limb Rehabilitation with Different Levels of Supervision
NCT06725784 · Phase: NA · Started 2025-03-04

Upper limb impairments are often a result of neurological or traumatic injuries (e.g., stroke, traumatic brain injuries). These impairments may decrease independence in performing activities of daily ...

Brissago, Switzerland · Lugano, Switzerland
Recruiting
Blood Extracellular Vesicles as Predictive Recovery Biomarker After Stroke and Brain Injury
NCT06871800 · Phase: Not specified · Started 2024-09-09

The rehabilitation outcome and recovery, in people after stroke or with vascular severe brain injury(vSBI), are difficult to predict. Moreover, the clinical management of patients during hospitalizati...

Florence, Italy · Milan, Italy · Torino, Italy
Recruiting
The Feasibility and Therapeutic Effect of Hybrid End-effector Robot-assisted Gait Training With an Active-assisted Modul
NCT07034521 · Phase: NA · Started 2025-08-12

Walking rehabilitation after stroke is most effective during the first three months of recovery, but even in the chronic phase-beyond six months post-stroke-a significant number of patients still show...

Taipei, Taipei, Taiwan
Recruiting
Biomarkers of Reaction To HIIT Exercise
NCT06059872 · Phase: NA · Started 2024-01-01

Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even ...

Decatur, Georgia, United States
Recruiting
Adherence to Home-Based Exercises in Musculoskeletal Disorders
NCT07261553 · Phase: Not specified · Started 2024-12-30

Home exercise program is recommended by physicians to patients and their relatives to do at home and It is a treatment option in which the physician describes how to do it. Home workout program to be ...

Konya, Konya, Turkey (Türkiye)
Recruiting
The Active Transition Home Post-Stroke Program
NCT06119230 · Phase: NA · Started 2024-02-01

Post-stroke participants will wear wearable sensors for one week at 1-week prior to discharge from inpatient rehabilitation, 3- and 7- weeks post-discharge and 3-months post-discharge. All participant...

Vancouver, British Columbia, Canada
Recruiting
Comparison Between LL Sesorimotor Training and WBB Therapy on PS, DB and FOF in Post Stroke Patients
NCT07642154 · Phase: NA · Started 2026-04-07

Stroke is a neurological disorder causing 70-80 percent deaths in the low income and developing countries. Patients commonly present with common impairments associated with balance, proprioception, po...

Lahore, Punjab Province, Pakistan
Recruiting
Error-enhanced Learning & Recovery in 2 & 3 Dimensions
NCT05180786 · Phase: NA · Started 2023-03-01

This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a targe...

Chicago, Illinois, United States · Chicago, Illinois, United States · Chicago, Illinois, United States
Recruiting
Home Tele Rehabilitation Therapy for Vascular Dementia
NCT06289569 · Phase: NA · Started 2024-12-14

To determine whether the home telerehabilitation therapy is feasible and lessens caregiver burden in chronic stroke patients with and without vascular dementia (VaD)...

Houston, Texas, United States
Recruiting
Implementation of a Home-based Computerized Cognitive Rehabilitation Program for Patients With ABI
NCT06749197 · Phase: NA · Started 2025-03-20

Rationale: Patients with acquired brain injury (ABI) may suffer from persistent cognitive deficits and/or subjective cognitive complaints, especially in the domains of attention and working memory. Co...

Rotterdam, South Holland, Netherlands
Recruiting
Using Immersive Virtual Reality for the Upper Limb Rehabilitation of Post-stroke Subjects
NCT06892886 · Phase: NA · Started 2023-03-01

Stroke produces brain damages that results in sensory, motor, and cognitive impairments which reduce the patient's quality of life and social participation. Upper limb recovery is a complex process wh...

Ferrara, Italy
Recruiting
Exploring Motor Learning in Acute Stroke Through Robotics
NCT04171856 · Phase: NA · Started 2020-01-01

The acute phase of stroke is characterized by an enhancement of neural plasticity which supports rapid motor recovery. It is unclear whether acute stroke patients can acquire new motor skills with the...

Yvoir, Namur, Belgium · Yvoir, Belgium
Recruiting
Nutritional Status in Subacute Stroke Patients Under Rehabilitation 2.0
NCT06096350 · Phase: Not specified · Started 2024-05-29

The Nutristroke study's findings revealed a malnutrition scenario in post-stroke patients undergoing rehabilitation. This has highlighted the significance of a correct nutritional status assessment up...

Roma, RM, Italy
Recruiting
Effectiveness of a Home-Based Rehabilitation Program in Stroke Survivors Using the Euleria Home® Device
NCT06968923 · Phase: NA · Started 2018-04-26

To verify the non-inferiority, in terms of post-treatment (T1) clinical effectiveness, of a "multidomain" telerehabilitation (TR) protocol compared to conventional outpatient rehabilitation in patient...

Verona, verona, Italy
Recruiting
Biofeedback as an Adjunctive Treatment for Post-stroke Dysphagia
NCT05591040 · Phase: NA · Started 2022-10-30

The aim of the study is to evaluate whether the effect of biofeedback treatment is more effective than a control treatment in the recovery of dysphagia. This study will be a multicentric randomized, ...

Venice-Lido, Italy
Recruiting
Mirror Therapy and Augmented Reality in Stroke Rehabilitation
NCT05993091 · Phase: NA · Started 2023-05-05

This research is in line with the National Health Research Institutes (NHRI) Innovative Research Grant priority to address innovative treatment strategies for neurological disorders that are in desper...

New Taipei City, Taiwan · New Taipei City, Taiwan · Taichung, Taiwan
Recruiting
Passive Robots for Stroke Rehabilitation: A Feasibility Study
NCT07218276 · Phase: NA · Started 2025-11-05

The purpose of this study is to examine the feasibility and effectiveness of a novel, multimodal approach that combines passive devices with noninvasive neuromuscular stimulation for upper extremity r...

Ann Arbor, Michigan, United States
Recruiting
A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
NCT02098265 · Phase: NA · Started 2010-06

The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke...

Madison, Wisconsin, United States
Recruiting
Effect of Shoulder Sling Use on Balance and Mobility in Subacute Stroke Patients
NCT06904768 · Phase: NA · Started 2025-03-13

This study examines whether wearing a shoulder sling can improve balance and mobility in people who are recovering from a stroke. Participants will perform simple movement and balance tests twice-once...

Koropí, Attica, Greece
Recruiting
Virtual Reality Rehabilitation for Stroke Patients in the Hospital and at Home.
NCT06864741 · Phase: NA · Started 2025-10-15

The goal of this clinical trial is to test whether a low-cost virtual reality (VR) motor rehabilitation platform can improve motor recovery in people recovering from a first-time ischemic stroke both ...

Kentville, Nova Scotia, Canada
Recruiting
The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission f
NCT06922409 · Phase: NA · Started 2025-04-10

Background: Light is the most important regulator of circadian rhythm. Naturalistic light, which contains the spectrum of sunlight throughout the day, has been shown to have a positive impact on ment...

Glostrup Municipality, Capital Region, Denmark
Recruiting
Meditation and Biofeedback to Improve Anxiety, Depression and Quality of Life in Inpatients After Stroke
NCT05845541 · Phase: NA · Started 2023-12-01

The goal of this clinical trial is to investigate the impact of a technology-based meditation program in the inpatient stroke population. It will explore how this approach can support patient-centred,...

Toronto, Ontario, Canada
Recruiting
Telerehabilitation In The Home After Stroke
NCT06682429 · Phase: NA · Started 2025-08-22

The purpose of this research study is to evaluate whether telerehabilitation targeting arm movement, when added to usual care, improves arm function and reduces global disability after stroke, compare...

Downey, California, United States · Irvine, California, United States · Los Angeles, California, United States
Recruiting
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
NCT06638944 · Phase: PHASE2 · Started 2025-07-22

Dysphagia, or difficulty swallowing, is a common symptom of many neurological diseases but its treatment is not well established or easily accessible. To start addressing this gap, the researchers de...

West Lafayette, Indiana, United States
Recruiting
FIND Stroke Recovery - A Longitudinal Study
NCT05708807 · Phase: Not specified · Started 2018-02-01

Stroke survivors frequently suffer disabilities including motor and cognitive problems, impairments in speech and vision, depression, and several other disabilities that worsen their quality of life. ...

Gothenburg, Sweden
Recruiting
Hybrid Stroke Rehab With Mirror Priming
NCT07324278 · Phase: NA · Started 2025-12-30

This trial aims to examine the effects of enhanced mirror priming, overcoming the limitations of traditional mirror therapy, to achieve optimization and personalized intervention....

Kaohsiung City, Yanchao District, Taiwan
Recruiting
Prognostic Factors to Regain Consciousness
NCT04445649 · Phase: Not specified · Started 2020-06-15

The study aims to identify factors that predict the medium and long-term outcome of patients with disorders of consciousness (DOC) undergoing early neurological rehabilitation. In this prospective, o...

Hessisch Oldendorf, Germany
Recruiting
Playing Piano to Improve Hand Function Early After Stroke
NCT06621771 · Phase: NA · Started 2024-10-15

The goal of this clinical trial is to study the feasibility of a 6-week piano playing training intervention in a subacute stroke population. More specifically, the investigators aim to (1) implement a...

Laval, Quebec, Canada
Recruiting
Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)
NCT04119544 · Phase: NA · Started 2019-12-10

Hemiparesis is a common motor disorder after a stroke. The majority of patients do not recover functional use of their paretic upper limb. The use of mirror therapy allows the activation of the mirro...

Reims, Champagne-Ardenne, France · Saint-Paul-lès-Dax, New Aquitaine, France · Boissise-le-Roi, France
Recruiting
Emotional Recovery Post-Stroke
NCT06782321 · Phase: NA · Started 2025-05-01

The purpose of this study is to evaluate whether adding an emotional wellness component to occupational therapy (OT) and/or speech therapy (ST) telerehabilitation improves overall emotional well-being...

Charleston, South Carolina, United States
Recruiting
Proprioceptive Error Correction for Post-Stroke Upper Limb Rehabilitation
NCT07156955 · Phase: NA · Started 2025-10-13

The investigators aim to develop sensory transformation and augmentation technologies that minimize the impact of proprioceptive errors, thereby significantly enhancing motor learning and rehabilitati...

Seoul, Seoul, South Korea
Recruiting
Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
NCT05887440 · Phase: NA · Started 2023-08-21

The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust....

Rennes, France
Recruiting
Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (
NCT07036406 · Phase: PHASE2 · Started 2025-07-28

The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+M...

New York, New York, United States
Recruiting
Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors
NCT02896348 · Phase: NA · Started 2025-02-26

The goal of this study is to: 1. Assess the usability of the SynPhNe device in a home environment. 2. Evaluate the efficacy of the SynPhNe home use device to improve motor hand function in chronic st...

Boston, Massachusetts, United States
Recruiting
EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
NCT05628324 · Phase: NA · Started 2024-07-31

The purpose of this study is to develop and test if upper limb task practice and muscle activity training improve upper limb function in stroke survivors. Participants will be asked to come to the lab...

Charleston, South Carolina, United States
Recruiting
Sleep and Motor Learning in Stroke
NCT05746260 · Phase: Not specified · Started 2023-03-01

This study will explore whether sleep disruption in the sub-acute phase of stroke explains variation in clinical motor outcomes, and whether this relationship is mediated by variation in behavioural m...

Oxford, United Kingdom
Recruiting
Virtual Reality Mirrors Therapy Usability
NCT07039136 · Phase: NA · Started 2025-06-28

Mirror therapy has been shown to support motor recovery by stimulating neural mechanisms through visual feedback. Recent technological advancements, particularly in virtual reality (VR), have enabled ...

Bolu, Merkez, Turkey (Türkiye) · Bolu, Turkey (Türkiye)
Recruiting
Diaphragm Morphology and Respiratory Muscle Strength in Subacute Hemiplegic Patients
NCT07447804 · Phase: Not specified · Started 2026-02-26

The aim of this study is to determine the relationship between diaphragm morphology (diaphragm excursion, end-inspiratory and end-expiratory diaphragm thickness, and thickening fraction) and respirato...

Istanbul, Ataşehir, Turkey (Türkiye)
Recruiting
Effectiveness and Safety of At-home Gait Rehabilitation Using Wearable Exoskeletal Robot
NCT06543758 · Phase: PHASE4 · Started 2024-08-01

The goal of this clinical trial is to evaluate the effectiveness and safety of a home-based robotic-assisted gait rehabilitation service using a wearable exoskeletal robot for stroke patients. The ma...

Yongin-si, Gyeonggi-do, South Korea
Recruiting
Dynamic Perturbation Training for Home-Based Upper Limb Rehabilitation in Chronic Stroke
NCT06992700 · Phase: NA · Started 2025-03-15

Study procedures: After acquiring clinical-demographic, neurophysiological and clinical-functional data to describe the extent of upper limb impairment at baseline at the facilities of the Rehabilitat...

Ferrara, Emilia-Romagna, Italy
Recruiting
Tolerance Study of Robotic-Assisted Virtual Reality Walking Rehabilitation for Non-Walking Stroke Patients
NCT06053619 · Phase: NA · Started 2023-11-20

The primary objective of this study is to evaluate the tolerance of the use of immersive virtual reality (VR) during robotic walking rehabilitation sessions by Gait Trainer (GT) in post-stroke patient...

Limoges, France
Recruiting
The Effect of Modified Constraint Induced Movement Therapy on Upper Extremity Function in Stroke Rehabilitation
NCT06692569 · Phase: NA · Started 2024-11-12

The purpose of the study is to determine the effect of Modified Constraint-Induced Movement Therapy and trunk restraint contrasted with conventional physical therapy treatment on improving upper extre...

Riyadh, Riyadh Region, Saudi Arabia
Recruiting
Effects of Rhythmic Auditory Cueing Augments Cognitive Treadmill Walking Training in Individuals With Chronic Stroke
NCT06392945 · Phase: NA · Started 2024-05-24

The first objective of this study is to examine the superiority of the combined rhythmic auditory cueing with cognitive treadmill training (combined group) in people with stroke as compared with the c...

Taipei, Taiwan
Recruiting
Comparative Study of LoKomat® Exoskeleton VS C-Mill® Treadmill for Gait Recovery in Rehabilitation.
NCT07230470 · Phase: NA · Started 2025-12-09

The use of robotic technology for the treatment of gait in neurological pathologies has provided different results in scientific evidence. In patients with some types of acquired brain damage, such as...

Salamanca, Spain
Recruiting
Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
NCT04477330 · Phase: NA · Started 2020-09-01

Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using b...

Chicago, Illinois, United States
Recruiting
Powering Up Stroke Rehabilitation Through HIIT
NCT06554665 · Phase: NA · Started 2024-08-20

Objectives: To investigate the effects of high-intensity interval training (HIIT) on musculoskeletal fitness in chronic stroke survivors. Hypothesis to be tested: HIIT, performed on a recumbent stepp...

Kowloon, Hong Kong
Recruiting
Post-stroke Gait Rehabilitation Using the SHAJA-R Exoskeleton
NCT07035730 · Phase: NA · Started 2025-07-07

The goal of this clinical trial is to evaluate the safety, reliability, and short-term effectiveness of SHAJA-based training in improving walking velocity and endurance in post-stroke patients. The m...

Costa Masnaga, Italy, Italy · Pisa, Italy, Italy
Recruiting
MyHand 2: An Active Hand Orthosis for Stroke Patients
NCT04436042 · Phase: NA · Started 2020-03-06

This study is designed to further develop and test the hardware and software components of the MyHand device based on user feedback and results from our pilot study. The goal is to refine the device s...

New York, New York, United States
Recruiting
Goal Attainment Scaling in Upper Limb Spasticity Treatment
NCT04975646 · Phase: NA · Started 2021-01-03

Patients after stroke with upper limb spasticity treated with botulinum toxin-A (BTX-A) will be included in this two-part study. In the first part, goal attainment scaling and comprehensive assessment...

Ljubljana, Slovenia
Recruiting
Human-like Robotic Controllers for Enhanced Motor Learning
NCT04578665 · Phase: NA · Started 2021-07-13

The purpose of this study is to develop a new paradigm to understand how humans physically interact with each other at a single and at multiple joints, with multiple contact points, so as to synthesiz...

Chicago, Illinois, United States
Recruiting
Using tDCS in Speech-based Stroke Rehabilitation
NCT03452202 · Phase: NA · Started 2019-01-11

The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation...

New York, New York, United States · White Plains, New York, United States
Recruiting
Inpatient Stroke Recovery Using Sensors
NCT04219670 · Phase: Not specified · Started 2017-10-31

This observational trial seeks to assess the feasibility of using non-invasive, portable, real-time body-worn sensors to continuously monitor, quantify, and interpret recovery during inpatient treatme...

Chicago, Illinois, United States
Recruiting
MINT Conditioning to Improve Gait
NCT07041775 · Phase: NA · Started 2026-06-04

This study will test the ability of myoelectric interface for neurorehabilitation (MINT) training to improve walking function....

Chicago, Illinois, United States · Dallas, Texas, United States
Recruiting
Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observationa
NCT07253974 · Phase: Not specified · Started 2024-11-11

The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabili...

Barcelona, Spain
Recruiting
Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities
NCT07092293 · Phase: Not specified · Started 2025-02-11

This study aims to better understand how occupational therapists provide rehabilitation for adults recovering from stroke or spinal cord injury (SCI), with a focus on improving arm and hand function. ...

Columbus, Ohio, United States
Recruiting
The Effect of Extremely Low-Frequency Magnetic Field on Stroke Patients
NCT06551597 · Phase: NA · Started 2024-06-01

A stroke can cause neurological deficits resulting in decreased motor, sensory, and cognitive function, as well as a decline in psychosocial functioning. Early rehabilitation following a stroke incide...

Poznan, Poland
Recruiting
EMG Analysis in ABI: Motor Imagery and Action
NCT06230718 · Phase: NA · Started 2024-01-01

This study focuses on electromyographic analysis of upper limb muscle activation in stroke survivors during Motor Imagery (MI) and Action Observation (AO) rehabilitation techniques. By measuring muscl...

Salamanca, Salamanca, Spain
Recruiting
Art Therapy and Its Effect on Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery
NCT06709950 · Phase: NA · Started 2024-11-15

The target disease of this study is subacute ischemic stroke, a condition characterized by reduced blood flow to brain tissue due to arterial blockage, with a specific focus on the subacute recovery p...

Jiamusi, Heilongjiang, China
Recruiting
Lower Extremity Pressure Splints in HP
NCT06965894 · Phase: NA · Started 2025-05-13

Hemiplegia (weakness or paralysis on one side of the body) often impacts the lower extremities, making it challenging for patients to walk or move their legs effectively. This study aims to explore th...

Jounieh, Keserwan, Lebanon
Recruiting
High vs Low-frequency of High-intensity Training in Chronic Stroke
NCT06612723 · Phase: NA · Started 2024-09-16

The purpose of this pilot study is to investigate the potential role of training frequency on locomotor outcomes following high-intensity gait training and provision of a home walking program....

Indianapolis, Indiana, United States
Recruiting
Responses to Backward Walking Training Post-Stroke
NCT04928482 · Phase: NA · Started 2021-11-08

Approximately 15,000 Veterans are hospitalized for stroke each year with new cases costing an estimated $111 million for acute inpatient, $75 million for post-acute inpatient, and $88 million for foll...

Gainesville, Florida, United States · Jacksonville, Florida, United States
Recruiting
Early Robotic Gait Training After Stroke
NCT06430632 · Phase: NA · Started 2024-03-01

The ERA Stroke project will compare the effects of robotic gait training (RGT) and usual care (UC) gait training in patients in the subacute phase of stroke recovery undergoing inpatient rehabilitatio...

Dallas, Texas, United States
Recruiting
Cycle and Stroke With Biofeedback for Power Symmetry
NCT06857916 · Phase: NA · Started 2021-04-01

To determine changes in power symmetry, gait symmetry, and functional outcomes for participants' poststroke (Inpatient Rehabilitation Facility) after participating in an intervention using a recumbent...

Salt Lake City, Utah, United States
Recruiting
Sensory and Cognitive Outcomes of Robotic Exercises in Stroke (SCORES)
NCT06109324 · Phase: NA · Started 2023-11-13

Based on the findings of meta-analyses, upper limb robotic rehabilitation has shown to enhance daily living activities, motor function, and strength in stroke patients. However, when compared to tradi...

Florence, Italy · Messina, Italy · Roma, Italy
Recruiting
The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery
NCT07056049 · Phase: NA · Started 2025-07-13

Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world. Most stroke survivors will suffer from motor and cog...

Ofakim, Israel · Ofakim, Israel
Recruiting
A Feasible Smart Upper Limb Rehabilitation Model for Patients With Stroke and Spinal Cord Injuries
NCT06215625 · Phase: NA · Started 2024-01

The goal of this clinical trial is to investigate the effectiveness of the developed application and exoskeleton robot devices for home-based training in stroke patients and patients with spinal cord ...

Tainan, Taiwan · Tainan, Taiwan
Recruiting
Effectiveness of the Cognitive Orientation to Daily Occupational Performance (CO-OP)
NCT06919315 · Phase: NA · Started 2025-05-02

The goal of this clinical study is to examine the effectiveness of the Cognitive Orientation to daily Occupational Performance (CO-OP) in adults (18+) with accuired brain injury when applied in Danish...

Skive, Denmark · Viborg, Denmark
Recruiting
Task-Oriented Upper Limb Training With Focal Vibration in Stroke
NCT07558876 · Phase: NA · Started 2026-04-27

This study aims to investigate the effects of task-oriented upper limb training combined with focal vibration on hand function, proprioception, and muscle tone in patients with stroke. Participants wi...

Seoul, South Korea · Seoul, South Korea
Recruiting
Turkish Validity and Reliability of the Expanded Rehabilitation Complexity Scale
NCT06573359 · Phase: Not specified · Started 2024-08-24

The RCS is a tool that can assess the need for complex rehabilitation and objectively indicate that a patient may have difficulty functioning well at home or in the community if their medical needs ar...

Istanbul, Bahçelievler, Turkey (Türkiye)
Recruiting
Evaluation of the Impact of the AVanCer Program Provided by the ARRPAC Day Center
NCT05795686 · Phase: NA · Started 2023-06-20

In France, more than 150,000 strokes occur each year. Stroke is a major risk factor for dependency, representing the leading cause of acquired non-traumatic disability in adults. Head injuries, which ...

Bron, France
Recruiting
Robot-assisted Versus Conventional Physical Therapy for Hand in Sub-acute Stroke
NCT07615569 · Phase: NA · Started 2026-05-22

This randomized controlled trial aims to compare the effectiveness of robotic-assisted physiotherapy and conventional physiotherapy in improving hand function among patients with sub-acute stroke. Str...

Lahore, Punjab Province, Pakistan
Recruiting
Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients
NCT07254195 · Phase: NA · Started 2026-02-25

Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of pat...

Saint-Genis-Laval, Lyon, France
Recruiting
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spec
NCT06806397 · Phase: Not specified · Started 2024-06-26

The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional n...

Moscow, Russia · Moscow, Russia
Recruiting
Efficacy and Acceptability of the Luna EMG Rehabilitation Robot on Motor Recovery of the Upper Limb in the Chronic Phase
NCT05902910 · Phase: NA · Started 2023-06-12

Recent work on large cohorts of chronic stroke (\>6 months post-stroke) have shown that intensive training of the upper limb in the chronic stroke patients can lead to substantial motor and functional...

Brest, France
Recruiting
Effects of Action Observation Therapy Based on Virtual Reality for Upper Extremity Rehabilitation in Stroke
NCT06196229 · Phase: NA · Started 2023-11-25

This study aims to conduct a randomized controlled trial (RCT) assessing the effectiveness of combining Action Observation (AO) with Virtual Reality (VR) in improving upper limb function for stroke pa...

Lahore, Punjab Province, Pakistan
Recruiting
Clinical Relevance of the HD sEMG Signals in the Post-stroke Rehabilitation
NCT05849896 · Phase: NA · Started 2023-03-13

The goal of this clinical trial is to learn about the WPM-SEMG-V2 device (Wireless Portable and Multi-Channel, WPM) designated to acquire high-density (HD) surface electromyography (sEMG) signals in h...

Lugano, Switzerland
Recruiting
Substrates for Post-Stroke Arm Rehabilitation
NCT06998485 · Phase: NA · Started 2025-10-07

Difficulty moving the arm is very common and a major cause of disability after stroke. Although rehabilitation therapies (i.e., occupational and physical therapy) are the most common treatments used t...

Boston, Massachusetts, United States
Recruiting
Real-time Personalized Brain State-dependent TMS After Stroke
NCT06533176 · Phase: NA · Started 2024-08-01

Transcranial magnetic stimulation (TMS) interventions could feasibly strengthen residual corticospinal tract (CST) connections and enhance recovery of paretic upper extremity function after stroke. Th...

Iowa City, Iowa, United States
Recruiting
Engaging Mobile Prism Adaptation Treatment at Home
NCT05595668 · Phase: NA · Started 2023-09-15

Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space. This condition has been linked to reduced ...

Bedford, Nova Scotia, Canada · Halifax, Nova Scotia, Canada · Halifax, Nova Scotia, Canada
Recruiting
R3THA Rehabilitation Feasibility and Usability Study
NCT06854978 · Phase: NA · Started 2024-03-27

The purpose of this study is to assess how the Rehabilitation Technologies for Hand and Arm (R3THA) device can be used for rehabilitation of people with stroke. the study will evaluate the feasibility...

West Orange, New Jersey, United States
Recruiting
Effects of rTMS Combined With Dual-Task Gait Training on Walking and Cognition After Stroke
NCT07356687 · Phase: NA · Started 2026-01-21

This randomized, double-blind, placebo-controlled trial will investigate whether repetitive transcranial magnetic stimulation (rTMS) applied to the dorsolateral prefrontal cortex (DLPFC) can enhance t...

Hong Kong, HongKong, Hong Kong
Recruiting
Exercise Primed Stroke Rehabilitation
NCT04877444 · Phase: EARLY_PHASE1 · Started 2021-07-01

Stroke is a leading cause of disability in the U.S. and many Veteran stroke survivors live with severe disability. Despite recent advances in rehabilitation treatments many stroke survivors have persi...

Charleston, South Carolina, United States
Recruiting
Implementation of a HABIT-ILE Intervention at Home for Chronic Stroke
NCT05727111 · Phase: NA · Started 2023-05-01

This study will use a randomized controlled trial design to assess the possible difference between two intensive treatment programs: a classic "Hand and Arm Bimanual Intensive Therapy Including Lower ...

Brussels, Belgium
Recruiting
Pulse Wave Velocity and in Subacute Stroke Patients Following Rehabilitation
NCT06224517 · Phase: Not specified · Started 2024-02-01

Currently, the literature regarding the relationship between Pulse Wave Velocity (PWV) and functional recovery, particularly of upper limb function, in patients with subacute stroke is still limited. ...

Taipei, Taiwan
Recruiting
Evolution of Walking Abilities in Subacute Stroke Patients Hospitalized in Neurorehabilitation Center
NCT06327035 · Phase: Not specified · Started 2024-03-26

The goal of this observational study is to describe the evolution of gait recovery during the subacute phase of stroke up to six months after stroke, in patients hospitalized in medical and neurologic...

Granville, Normandy, France · Boissise-le-Roi, France · Boissise-le-Roi, France
Recruiting
Strategy Training for Optimizing Attention for Individuals With Spatial Neglect
NCT07331896 · Phase: NA · Started 2026-04-06

It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect). Individuals with neglect have difficulty paying attention to one side o...

Pittsburgh, Pennsylvania, United States
Recruiting
Spatial-Motor Stroke-Rehab Study
NCT06053320 · Phase: NA · Started 2023-04-11

The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction....

Atlanta, Georgia, United States · Atlanta, Georgia, United States · Atlanta, Georgia, United States
Recruiting
Nature-based Therapies in Stroke Rehabilitation
NCT05898542 · Phase: NA · Started 2023-05-31

Stroke rehabilitation patients are subjected to additional nature-based therapies during a rehabilitation ward period....

Lahti, Finland
Recruiting
Rehabilitation of Visual Function After Brain Injury
NCT03160131 · Phase: NA · Started 2017-08-01

In Denmark, about 120,000 people suffer from brain damage, of whom approx. 75,000 with brain damage after stroke. Serious and often lasting vision impairments affect 20% to 35% of people after stroke....

Copenhagen, Hellerup, Denmark
Recruiting
Evaluation of a Haptic Glove for Assessing Tactile Perception in Post-Stroke Patients
NCT06643273 · Phase: NA · Started 2024-10-04

The aim of the SCORES Haptic Glove Study is to assess the technical features, safety, and reliability of a sensor-equipped glove designed to evaluate tactile perception. This will help guide further t...

Florence, Italy, Italy · Messina, Italy, Italy · Roma, Italy, Italy
Recruiting
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
NCT06633146 · Phase: NA · Started 2024-06-01

Outpatient participants with a recent stroke diagnoses receive complimentary rehabilitation. The nature interventions include ergo- and physiotherapeutic and neurocognitive tasks with the support of a...

Lahti, Finland
Recruiting
Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in
NCT07523503 · Phase: NA · Started 2026-04-05

This randomized clinical trial will examine upper limb rehabilitation in individuals recovering from stroke. The study will compare unilateral and bilateral task-oriented training approaches to determ...

Kot Addu, Pakistan
Recruiting
Cryoneurolysis for Knee and Shoulder Pain in an Inpatient Setting
NCT05674604 · Phase: Not specified · Started 2022-10-10

The purpose of the study is to measure the outcomes of a standard care, an ultrasound guided mini-invasive percutaneous procedure, performed on recent stroke patients on reduces pain, increases functi...

Victoria, British Columbia, Canada
Recruiting
Cognition and Motor Learning Post-stroke
NCT04829071 · Phase: EARLY_PHASE1 · Started 2023-01-16

This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this...

Los Angeles, California, United States
Recruiting
Does High-intensity Exercise Lead to Better Functional Outcomes Early After Stroke in an Inpatient Rehabilitation Settin
NCT06913127 · Phase: NA · Started 2025-01-20

The purpose of this study is to find out the effectiveness of high intensity exercise (HIE) early after stroke, this study is hoping to recruit 36 participants in total and will be analysing pre- and ...

Singapore, Singapore
Recruiting
Clinical Validation of an Instrumented Glove for Sensorimotor Rehabilitation
NCT06649968 · Phase: NA · Started 2024-10-21

The goal of this clinical trial is to evaluate the DESC-Glove, an instrumented glove developed for sensorimotor rehabilitation in individuals recovering from a stroke, utilizing non-invasive vibration...

Acerenza, Italy · Milan, Italy · Roma, Italy
Recruiting
Effect of Sensorimotor Training Versus Dual-task Training
NCT07628374 · Phase: NA · Started 2026-04-20

The aim of this study is to determine the comparative effects of sensorimotor training and dual-task training on propriocetion, balance, functional mobility and fall risk in stroke patients....

Rajanpur, Punjab Province, Pakistan
Recruiting
A Caregiver-Assisted Rehabilitation With Strategy Training (CAR-ST) for Stroke Patients
NCT06754566 · Phase: NA · Started 2025-01-17

The goal of this randomized controlled trial is to examine if involving the caregivers in the strategy training (i.e. caregiver-assisted rehabilitation with strategy training, CAR-ST) works to improve...

New Taipei City, Taiwan · New Taipei City, Taiwan · Taipei, Taiwan
Recruiting
Comprehensive Intensive Stroke Rehabilitation
NCT05323916 · Phase: NA · Started 2022-05-01

In this study, the investigators aim to assess the effectiveness of the Comprehensive Intensive Rehabilitation Program After Stroke implementing the International Classification of Functioning, Disabi...

Prague, Czechia
Recruiting
Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits
NCT05296408 · Phase: NA · Started 2022-04-01

This study will evaluate the effects of combining motor learning-based therapy with use of the MyoPro , a wearable exoskeletal myoelectrically controlled orthotic device. MyoPro uses electromyographic...

Cleveland, Ohio, United States
Recruiting
COMPuter-assisted Self-training to Improve EXecutive Function
NCT04229056 · Phase: NA · Started 2020-06-01

This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Diseas...

Copenhagen, Denmark · Copenhagen, Denmark
Recruiting
Sensory-Motor Integration for Speech Rehabilitation in Patients with Post-stroke Aphasia
NCT04433351 · Phase: NA · Started 2022-05-05

SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging an...

Grenoble, France
Recruiting
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
NCT06930131 · Phase: NA · Started 2025-02-21

The postulate of this study is that rehabilitation combining linguistic and metacognitive training will result in a significant improvement in language performance correlated with changes in functiona...

Toulouse, France
Recruiting
Integrating AI in Stroke Neurorehabilitation
NCT07138495 · Phase: NA · Started 2025-10-15

The AISN multicenter randomized controlled trial will assess the effectiveness of a novel artificial intelligence (AI)-based clinical decision-support system integrated into the Rehabilitation Gaming ...

Limoges, France · Venice, Veneto, Italy · Cluj-Napoca, Romania
Recruiting
Unsupervised Therapy After Stroke in the Home Setting with a Hand Rehabilitation Device (ReHandyBot)
NCT06057129 · Phase: NA · Started 2023-11-13

The ReHandyBot is a robot for hand rehabilitation after stroke. The aims of this study are (1) to investigate the feasibility of unsupervised therapy with the ReHandyBot with stroke inpatients, first ...

Brissago, Canton Ticino, Switzerland
Recruiting
Robot-Assisted Training Versus Standard Training in Ischemic Stroke
NCT06273475 · Phase: NA · Started 2024-05-01

The aim of this randomised controlled trial (RCT) nested in a prospective cohort, is to investigate the superior effect of late-phase robot-assisted versus standard training on motor function, physica...

Copenhagen, Denmark · Odense, Denmark
Recruiting
Decoding Motor Imagery From Non-invasive Brain Recordings as a Prerequisite for Innovative Motor Rehabilitation Therapie
NCT06469463 · Phase: NA · Started 2026-03-17

Seminal studies in motor neuroscience involving healthy subjects have revealed time-locked changes in induced power within specific frequency bands. Brain recordings were shown to exhibit a gradual re...

Bron, France
Recruiting
The Effect of Motor Relearning Program on Functional Mobility in Stroke Rehabilitation.
NCT06690073 · Phase: NA · Started 2024-11-04

1. To find out the effectiveness of conventional physiotherapy on improving functional mobility of lower extremity among chronic hemiplegic subjects. 2. To find out the effcctiveness of motor relearni...

Riyadh, Riyadh Region, Saudi Arabia
Recruiting
Immersive Virtual Reality Treatment for Unilateral Spatial Neglect
NCT06366360 · Phase: NA · Started 2024-03-11

Unilateral Spatial Neglect (USN) is a relatively common neuropsychological syndrome following stroke. It is characterized by difficulties in detecting, orienting and identifying events located in the ...

Saint-Maurice, France
Recruiting
VIrtual Reality Glasses Use to Improve Lateropulsion and the Post-stroke Postural Vertical
NCT04911738 · Phase: NA · Started 2021-06-15

VIRGIL is a monocentric interventional study aiming to investigate the effect of immersion in a virtual tilted room on modulation of the verticality representation (postural vertical \[PV\] and visual...

Grenoble, France
Recruiting
Adaptive Trial Scheduling in Naming Treatment for Aphasia
NCT05653466 · Phase: PHASE2 · Started 2023-12-06

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of ...

Pittsburgh, Pennsylvania, United States
Recruiting
Body Composition, Frailty, and Function in Rehabilitation
NCT06527742 · Phase: Not specified · Started 2024-12-09

The investigators are investigating if body composition measures - in particular muscle mass, body fat, and something called the phase angle - are able to reliably predict functional outcomes for pati...

Singapore, Singapore, Singapore
Recruiting
Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments
NCT07404761 · Phase: NA · Started 2025-12-22

This is a multicenter, randomized, controlled clinical study evaluating the safety and effectiveness of the Spatial StimelMD (SSMD) device for upper-limb neuromotor rehabilitation in adults with impai...

Haifa, Israel
Recruiting
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
NCT06655636 · Phase: NA · Started 2024-12-04

The purpose of this study is to evaluate the safety, feasibility, and efficacy of an exoskeletal network of passive, multi-joint springs for forearm supination. Also known as the forearm ExoNET, the d...

Chicago, Illinois, United States
Recruiting
Informative of Surface Electromyography and Prognostic Factors in Assessing the Recovery of Balance and Gait After Strok
NCT04981184 · Phase: NA · Started 2019-07-22

The aim of the biomedical research is to determine the informativeness and prognostic factors of surface electromyography by assessing the probability of recovery of balance and gait parameters in the...

Kaunas, Lithuania
Recruiting
Virtual Reality Based Rehabilitation After Ischemic Stroke
NCT06401564 · Phase: NA · Started 2023-04-17

Use the template below as a guide to write a brief study description in plain language. Tailor the text that appears in brackets and yellow to your research study. To finalize, delete the text in ital...

Stony Brook, New York, United States
Recruiting
Improving Participation After Stroke Self-Management-Rehabilitation
NCT06588647 · Phase: NA · Started 2024-12-16

The overall goal of this proposed study is to evaluate the efficacy of a small-group, stroke-specific, self-management program delivered via telehealth to improve self-efficacy, activity performance, ...

Columbia, Missouri, United States
Recruiting
Optimal Intensity of Reactive Balance Training Post-stroke
NCT06555016 · Phase: NA · Started 2024-11-11

Falls in daily life are a serious risk for people with stroke. A new type of balance training, called reactive balance training (RBT). may help to reduce this risk of falling. In some previous studies...

Toronto, Ontario, Canada
Recruiting
Effects of Myoelectric Biofeedback on Upper Limb Function in Post-stroke Patients
NCT06443008 · Phase: NA · Started 2024-07-01

The purpose of this clinical trial is to investigate the effect of myoelectric biofeedback therapy on upper limb function in elderly patients with cerebral infarction, and to analyze the adjustment of...

Yiwu, Zhejiang, China
Recruiting
Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke
NCT03401762 · Phase: NA · Started 2018-01-15

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm...

Chicago, Illinois, United States
Recruiting
A Qualitative and Usability Evaluation of Advanced Technologies for Home Upper Limb Neurorehabilitation Post-stroke
NCT06406569 · Phase: NA · Started 2024-07-31

Due to limited resources such as the low therapist to patient ratio or high costs associated to rehabilitation therapy, providing higher therapy dose to patients after discharge is highly challenging....

Singapore, Singapore, Singapore
Recruiting
Sensory-Motor Rehabilitation Post Stroke
NCT02369770 · Phase: NA · Started 2019-04-26

Early after stroke, patients often have significant motor impairment and sensory deficit. Evidence has demonstrated heightened plasticity and significant recovery in the acute phase (first months) pos...

Baltimore, Maryland, United States
Recruiting
Visual Plasticity Following Brain Lesions
NCT07105358 · Phase: NA · Started 2025-07-17

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous ...

Washington D.C., District of Columbia, United States
Recruiting
Using Omnidirectional Virtual Reality and Treadmill Training for Chronic Stroke
NCT06495450 · Phase: NA · Started 2025-04-28

The primary objective of this pilot randomized controlled trial (RCT) is to test the feasibility (consent rate, retention rate, participant burden, adherence, technical issues, safety) and usability (...

Halifax, Nova Scotia, Canada
Recruiting
Telerehabilitation With Digital Technologies for the Continuum of Care of Stroke Patients
NCT06978413 · Phase: NA · Started 2025-05-20

The goal of the pragmatic study is to evaluate the effectiveness of a home-based telerehabilitation protocol for patients with post-stroke disabilities, compared to a home-based educational program. ...

Acerenza, Italy · Bari, Italy · Genova, Italy
Recruiting
The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke
NCT06653855 · Phase: NA · Started 2024-12

Physical therapists use dry static cupping for the treatment of many conditions, including spasticity for patients post-stroke. While research better describes the effects of dry static cupping for pa...

Joliet, Illinois, United States
Recruiting
Effectiveness of Isokinetic Exercises in Proprioception for Post-stroke Patients
NCT07106619 · Phase: NA · Started 2025-08-01

Somatosensory dysfunction including the sense of movement and position, i.e. proprioception, is observed in approximately 65% of patients after stroke. Loss of muscle strength, especially in the lower...

Ankara, Yenimahalle, Turkey (Türkiye)
Recruiting
Hemianopsia Rehabilitation After Stroke or Brain Injury
NCT06241209 · Phase: NA · Started 2024-01-25

In patients with hemianopsia following stroke or brain injury, we will determine if stimulating the visual field with images from a PowerPoint slide set can increase the visual field....

Edmonton, Alberta, Canada
Recruiting
Combined Effects Of Sensory Integration And Vestibular Exercises On Post-Stroke Patients
NCT06500611 · Phase: NA · Started 2024-07-10

The aim of this study is to determine the combined effects of sensory integration and vestibular exercise on dizziness, fall risk and quality of life....

Lahore, Punjab Province, Pakistan
Recruiting
Physical Capacity Building for Chronic Stroke
NCT07039305 · Phase: NA · Started 2025-08-05

Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery. Investigators believe ...

Charleston, South Carolina, United States
Recruiting
Aha BOOST Arm-hand BOOST Therapy to Enhance Recovery After Stroke: Clinical, Health Economic and Process Evaluation
NCT06517251 · Phase: NA · Started 2024-06-17

The overall aim of this study is to establish the clinical- and cost-effectiveness of the arm-hand BOOST therapy when delivered on top of the usual care program in the sub-acute phase post stroke and ...

Edegem, Antwerpen, Belgium · Ghent, Oost-Vlaanderen, Belgium
Recruiting
Efficacy and Sustainability of a Carepartner-Integrated Telerehabilitation Program for Persons With Stroke
NCT06655402 · Phase: NA · Started 2025-03-25

Stroke is a leading cause of long-term disability. Research has placed little emphasis on integrating care partners (CP) (family members) into the rehabilitation process without increasing negative ca...

Atlanta, Georgia, United States
Recruiting
Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome
NCT06805929 · Phase: Not specified · Started 2020-06-15

Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor funct...

Roma, Italy, Italy
Recruiting
Human-Machine System for the H2 Lower Limb Exoskeleton
NCT02114450 · Phase: NA · Started 2015-11-20

This research study will investigate the use of smart lower limb robotic exoskeleton (developed by the CSIC, Spain) in rehabilitation after stroke. It will compare robotic-assisted rehabilitation with...

Houston, Texas, United States · Houston, Texas, United States
Recruiting
Rehabilitation With Biofeedback for People After Stroke
NCT07333079 · Phase: NA · Started 2026-01-19

The aim of the research will be to evaluate rehabilitation using the biofeedback method in people after stroke....

Rzeszów, Poland
Recruiting
Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
NCT03980457 · Phase: NA · Started 2021-09-01

The goal of this study is to determine the efficacy of electromechanical exoskeleton-assisted gait training on rehabilitation functional outcomes in patients with stroke undergoing therapy in an in-pa...

Oklahoma City, Oklahoma, United States
Recruiting
Power Exercise for Stroke Recovery: The POWER Pilot Trial (POWER-P)
NCT06780995 · Phase: NA · Started 2025-09-15

Weakness is one of the most common consequences of stroke. For the over 750,000 Canadians living with stroke, many daily activities like standing from a chair, walking and balance not only require str...

Kelowna, British Columbia, Canada · Hamilton, Ontario, Canada
Recruiting
Home-based Vision Rehabilitation Guided by Brain Imaging
NCT07635329 · Phase: NA · Started 2026-07-01

The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance...

Washington D.C., District of Columbia, United States
Recruiting
Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors.
NCT07504276 · Phase: NA · Started 2026-03-31

This study aims to: * Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke. * Evaluate changes in cognitive function using standardized assessment tools....

Islamabad, Punjab Province, Pakistan
Recruiting
Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation
NCT05903235 · Phase: NA · Started 2024-03-13

The specific study aims will be: 1. To design and develop the hardware and software of the VR+MT and MR+MT systems. 2. To test the feasibility of the VR+MT and MR+MT systems from the patients and to ...

Taoyuan City, Taiwan
Recruiting
Combined Mirror Therapy and Soft Robotic Glove for Hand Recovery After Stroke
NCT07467915 · Phase: NA · Started 2026-04-08

Post-stroke hemiplegia frequently results in impaired upper limb function, which significantly affects independence and quality of life. Various rehabilitation approaches have been developed to improv...

Baghdad, Babylon, Iraq
Recruiting
Rehabilitation With and Without Robot and Allied Digital Technologies in Stroke Patients
NCT06547827 · Phase: NA · Started 2024-08-12

Rehabilitation after stroke often employs Robot and Allied Digital Technologies (RADTs), yet evidence on their effectiveness remains inconclusive due to study heterogeneity and limited sample sizes. ...

Acerenza, Italy · Bari, Italy · Genova, Italy
Recruiting
Robotic Rehabilitation of the Upper Limb in Subacute Stroke
NCT06839482 · Phase: NA · Started 2025-02-06

This multicenter international randomized controlled trial (RCT) evaluates the effectiveness of the Gloreha Sinfonia® robotic exoskeleton for upper limb rehabilitation in individuals with subacute pos...

Elkins Park, Pennsylvania, United States · Kladruby, Czechia · Lázně Bělohrad, Czechia
Recruiting
Rehabkompassen® - a Patient-centered Digital Follow-up Tool in the Post-stroke Continuum of Care
NCT04915027 · Phase: NA · Started 2020-08-26

Stroke is a leading cause of disability and with a heavy burden for the society. Despite the demands from 'Socialstyrelsen' of improving post-acute care, an effective structured follow-up to promote a...

Umeå, Sweden
Recruiting
Stroke Motor Recovery for the Hand and Fingers
NCT06604143 · Phase: NA · Started 2026-05-07

The goal of this clinical trial is to compare two rehabilitation methods to improve finger movements in people who have had a stroke. The main question it aims to answer is which of these two training...

Toronto, Ontario, Canada · Laval, Quebec, Canada · Montreal, Quebec, Canada
Recruiting
Gait Recovery in Patients After Acute Ischemic Stroke
NCT04824482 · Phase: NA · Started 2020-09-01

More than 80% of ischemic stroke (IS) patients have some walking disability, which restricts their independence in the activities of daily living. Physical therapy (PT) significantly contributes to ga...

Olomouc, Czechia
Recruiting
Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)
NCT05651945 · Phase: NA · Started 2023-01-20

This study examines the effectiveness of the cardiac rehabilitation program for stroke patients. The study will examine if patients with stroke, who receive cardiac rehabilitation in addition to their...

Edison, New Jersey, United States
Recruiting
Robot Aided Rehabilitation - Intervention
NCT02359253 · Phase: NA · Started 2018-10-14

Sensorimotor impairments following stroke often involve complex pathological changes across multiple joints and multiple degrees of freedom of the arm and hand, thereby rendering them difficult to dia...

Baltimore, Maryland, United States
Recruiting
Phase I Split-Belt Treadmill Dosing for Subacute Stroke
NCT07469163 · Phase: PHASE1 · Started 2026-03-01

After experiencing a stroke, many individuals encounter difficulties with walking and balance, which can significantly impact their independence. Recent studies have indicated that split-belt treadmil...

Calgary, Alberta, Canada
Recruiting
ENMS With Balance Feedback for Post-stroke Ankle-foot Rehabilitation
NCT04934787 · Phase: NA · Started 2021-07-01

In this work, a novel hybrid ankle-foot robot is designed for gait rehabilitation after stroke, i.e., exoneuromusculoskeleton with balance sensing feedback (ENMS-BSF) by integrating the advantages of ...

Hong Kong, China
Recruiting
Robotic Evaluations of Motor Learning During Stroke Neurorehabilitation
NCT05106140 · Phase: Not specified · Started 2021-09-20

The RELEARN trial is a a prospective longitudinal cohort study sampled by convenience. Stroke survivors and healthy control individuals will be recruited to analyze motor learning in the upper extremi...

Calgary, Alberta, Canada · Calgary, Alberta, Canada · Calgary, Alberta, Canada
Recruiting
Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients
NCT06704074 · Phase: NA · Started 2026-04-05

Stroke rank second among the top causes of death, affecting millions of people in the worldwide. It has been reported that hemiplegia is the most common sequelae after stroke, accounting for about 50%...

Jinan, Shangdong, China
Recruiting
Task-Specific Self-Rehabilitation Training (TASSRET) Trial
NCT07208422 · Phase: NA · Started 2025-06-07

The goal of this pilot RCT is to evaluate the effectiveness of a Task-specific Self-rehabilitation Training (TASSRET) program and compare the effect of the two formats of the TASSRET (video vs manual)...

Kano, Nigeria
Recruiting
Finger Movement Training After Stroke
NCT05621980 · Phase: NA · Started 2023-09-05

Human development as a species has been strongly associated with the ability to dexterously manipulate objects and tools. Unfortunately, current therapy efforts typically fail to restore fine manual c...

Raleigh, North Carolina, United States
Recruiting
Effectiveness of Robot-Assisted Structured Foot-Ankle Sensorimotor Training in Stroke Patients
NCT07091045 · Phase: NA · Started 2026-03-01

Introduction: Stroke is a leading cause of long-term disability worldwide. Persistent lower-extremity motor and somatosensory impairments after stroke commonly limit walking and balance despite rehabi...

Istanbul, Istanbul, Turkey (Türkiye) · Istanbul, Turkey (Türkiye)
Recruiting
Soft Robot for Rehabilitation of Hand Function After Stroke
NCT07329075 · Phase: NA · Started 2026-01

The goal of this clinical trial is to investigate the feasibility of using the Soft Forearm Robot system for wrist and forearm recovery of hemiplegic subjects suffered from stroke. Participant will a...

Hong Kong, Hong Kong
Recruiting
Robot Aided Rehabilitation - Multi-joint Evaluations
NCT02359812 · Phase: Not specified · Started 2018-05-07

Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished...

Baltimore, Maryland, United States
Recruiting
Perceptions of RehAtt Mixed Reality System
NCT06641336 · Phase: NA · Started 2024-10-11

The study aims to explore the patients' perspective on usability and feasibility of the RehAtt™ mixed-reality system during upper limb, gait and balance function rehabilitation....

Ljubljana, Slovenia
Recruiting
Rehabilitation of Upper Limbs After Stroke
NCT07450274 · Phase: NA · Started 2026-03-02

The aim of the research will be to evaluate the effects of upper limb rehabilitation using modern Pablo Tyromotion technologies in people after stroke in the late period....

Rzeszów, Poland
Recruiting
Telerehabilitation for Aphasia (TERRA)
NCT04682223 · Phase: NA · Started 2021-05-05

Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery. The goal...

Columbia, South Carolina, United States
Recruiting
Effects Of Functional Action Observation With Auditory Cueing In Stroke Patients
NCT07428824 · Phase: NA · Started 2025-11-05

This study aims to determine the effects of functional action observation therapy with and without rhythmic auditory cueing on balance and gait in patients with stroke. A randomized clinical trial wi...

Lahore, Punjab Province, Pakistan · Lahore, Punjab Province, Pakistan
Recruiting
Vision on the Road: Vision Rehabilitation for Driving After Stroke
NCT07147660 · Phase: NA · Started 2025-03-28

The goal of this clinical trial is to learn if vision training works to improve functional vision in people with visual field loss after stroke. The investigators want to know more about how people pe...

Kongsberg, Norway · Oslo, Norway
Recruiting
The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Rehabilitation
NCT07299162 · Phase: NA · Started 2025-08-15

Stroke ranks second among the leading causes of death worldwide and third among the causes of disability. In stroke patients, motor impairment typically affects facial movements and the upper and lowe...

Istanbul, Bahçelievler, Turkey (Türkiye)
Recruiting
Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction
NCT06876597 · Phase: NA · Started 2025-04-08

This study aims to investigate the effects of motor-cognitive interactive robot-assisted training on improving upper limb motor dysfunction after stroke. By observing different combinations of motor a...

Fuzhou, China
Recruiting
Integration and Interactions Between Visual and Proprioceptive Feedbacks
NCT06931509 · Phase: NA · Started 2025-11-25

Mental imagery is a rehabilitation technique for stroke patients, involving the mental representation of movement. Recent technical advancements have enabled the use of visual, proprioceptive, and mix...

Saint-Etienne, France, France
Recruiting
Effects on Subacute Stroke With Robotic Assistive Gait Training
NCT07040215 · Phase: NA · Started 2025-07-01

The goal of this randomized controlled trial is to learn about the effects of Robotic Assisted Gait Training (RAGT) combined with traditional physical therapy in subacute stroke patients. The main que...

Changhua, Taiwan, Taiwan
Recruiting
Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke
NCT04446273 · Phase: NA · Started 2020-07-03

This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority r...

Taipei, Taipei, Taiwan · New Taipei City, Taiwan · Taichung, Taiwan
Recruiting
Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE)
NCT06885502 · Phase: NA · Started 2025-02-21

This study is a multicentric randomized controlled trial evaluating the effectiveness of digital technology, specifically a smartphone with integrated VR-and AR-based intervention, for at-home rehabil...

Cluj-Napoca, Romania · Tarragona, Spain
Recruiting
Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke
NCT06400186 · Phase: NA · Started 2024-08-15

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-rel...

Chicago, Illinois, United States · Hines, Illinois, United States
Recruiting
Virtual Reality and Field Training to Enhance Community Walking After Stroke
NCT04559373 · Phase: NA · Started 2021-04-01

While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited. The investigators propose to test a novel, low...

Laval, Quebec, Canada · Québec, Quebec, Canada
Recruiting
Effects of Intensive Virtual Reality-Based Balance and Gait Training on Activity Performance and Quality of Life in Suba
NCT07431151 · Phase: NA · Started 2026-02-01

Stroke is one of the leading causes of long-term disability worldwide, and balance and gait impairments are common in the subacute phase, limiting activity performance and quality of life. Early and i...

Ankara, Çankaya, Turkey (Türkiye)
Recruiting
The Effects of the Control Strategies of Wearable Lower Limb Rehabilitation Robots
NCT07037849 · Phase: NA · Started 2024-10-23

Post-stroke patients were required to complete a session of robot-assisted training, which involved nine repetitions of 5-meter overground walking (three trials for each of the three controllers) in a...

Shenzhen, Guangzhou, China
Recruiting
Bimanual Motor Skill Learning in Acute Stroke
NCT05760846 · Phase: NA · Started 2023-04-17

The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairmen...

Yvoir, Namur, Belgium · Yvoir, Belgium
Recruiting
Effectiveness of an mHealth Intervention, Based on Rehabilitation and a Personalised Nutrition Plan, in the Recovery and
NCT07267468 · Phase: NA · Started 2026-01-30

The goal of this clinical trial is to evaluate the efficacy of an mHealth intervention as a complement to usual clinical practice for the improvement and recovery of dysphagia in patients who have suf...

Algeciras, Cadiz, Spain
Recruiting
A Novel Rehabilitation Approach: Dyadic Strategy Training for Stroke Survivors and Their Caregivers
NCT05571150 · Phase: NA · Started 2022-10-05

The purpose of this study is to examine the efficacy of a newly developed dyad-focused strategy training intervention on enhancing participation of stroke survivors and their caregivers. To address t...

Taipei, Taiwan
Recruiting
Stroke Motor Rehabilitation and Recovery Study
NCT03485040 · Phase: Not specified · Started 2017-06-09

SMaHRT (Stroke Motor reHabiliation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic and hemorrhagic stroke....

Boston, Massachusetts, United States
Recruiting
Effects of Group Leisure Activities and Musical Training on Hospital Stroke Rehabilitation.
NCT07541560 · Phase: NA · Started 2025-12-01

The goal of this clinical trial is to learn whether adding group leisure activities and musical training can help people recover better after a stroke during their hospital rehabilitation. The study w...

Barcelona, Catalonia, Spain
Recruiting
Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
NCT05653440 · Phase: PHASE2 · Started 2023-11-27

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of ...

Pittsburgh, Pennsylvania, United States
Recruiting
Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling
NCT06008743 · Phase: NA · Started 2022-09-21

Stroke is the third leading cause of death and the primary cause of long-term disability in the United States, affecting approximately 795,000 people each year. Hemiparesis, or unilateral weakness, is...

Newark, Delaware, United States
Recruiting
Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke
NCT07598435 · Phase: NA · Started 2026-01-19

Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ...

Faisalābad, Punjab Province, Pakistan
Recruiting
Virtual Reality-Integrated Propulsion Feedback for Stroke Rehab
NCT07087743 · Phase: NA · Started 2025-07-25

This study evaluates a novel Virtual Reality (VR)-integrated visual feedback system designed to enhance limb propulsion during robot-assisted gait rehabilitation in individuals post-stroke. In collabo...

Galveston, Texas, United States
Recruiting
Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation
NCT05983185 · Phase: NA · Started 2023-02-01

After a right brain stroke, \>50% of Veterans experience problems with dressing, eating, self-care or steering their wheelchairs because their ability to move, orient, and respond toward the left side...

West Haven, Connecticut, United States · Decatur, Georgia, United States · Leeds, Massachusetts, United States
Recruiting
ORal-motor Assessment and Rehabilitation Mobile App (ORAR App)
NCT06635187 · Phase: Not specified · Started 2024-05-01

The goal of this study is to set up a database of oral-motor and speech functions of post-stroke patients in Hong Kong via an artificial intelligence-powered mobile-health application. The main study ...

Hong Kong, Hong Kong, Hong Kong
Recruiting
Digital Mirror Therapy in Stroke Rehabilitation
NCT07460128 · Phase: NA · Started 2026-03-02

Background: While conventional mirror therapy is a Level A recommended rehabilitation for poststroke upper extremity recovery, digital mirror therapy-enabled by augmented reality and computer vision-o...

Hong Kong, Hong Kong · Hong Kong, Hong Kong
Recruiting
Applicability of Robotic Devices, Virtual and Augmented Reality in the Rehabilitation of People With Stroke During Tread
NCT07350798 · Phase: NA · Started 2025-08-01

* Objective assessment of clinical symptoms, mobility and quality of life changes resulting from stroke and determination of changes resulting from therapies. * Assessment of the rehabilitation effect...

Kaposvár, Somogy County, Hungary
Recruiting
Virtual Reality Based Mirror Therapy
NCT06152328 · Phase: NA · Started 2024-04-01

The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation....

Bolu, Merkez, Turkey (Türkiye)
Recruiting
Financial Abilities in Neurological Diseases. Development of a Telerehabilitation Program: FINAGE
NCT05826548 · Phase: NA · Started 2021-03-11

Financial Abilities (FA) are a set of capacities that allow a person to independently manage her/his financial affairs in a manner consistent with personal self-interests and values. This project will...

Lido, Venezia, Italy
Recruiting
Individualized Exercise Prescription With a Data-driven Approach in Individuals With Stroke
NCT06878677 · Phase: NA · Started 2024-07-01

The goal of this clinical trial is to evaluate if the exercised via data-driven approach is effective in enhance the gait pattern in people with stroke. It will reduce burdun of patient consultations ...

Hksar, Hong Kong
Recruiting
Wearable Robotic and Virtual Reality on Hand in Stroke
NCT07287059 · Phase: NA · Started 2025-12-20

Stroke is a common neurological disorder resulting from acute focal damage to the central nervous system due to vascular events such as cerebral infarction, intracerebral hemorrhage, or subarachnoid h...

Istanbul, Beykoz, Turkey (Türkiye)
Recruiting
Post-stroke Nurse-led Rehabilitation to Improve Functional Activity and Community Participation in Bangladesh
NCT07384650 · Phase: NA · Started 2026-02-05

Stroke causes various levels of disability which decreases physical function for a prolonged period. The purpose of this study is to evaluate the effectiveness of a nurse-led rehabilitation program in...

Dhaka, Dhaka Division, Bangladesh
Recruiting
Effects of Mental Imagery Training Combined With Task Oriented Training by EMG-Driven Soft Robotic Hand Stroke in Stroke
NCT07629011 · Phase: NA · Started 2026-04-01

This randomized controlled trial is to determine the effects of robotic hand training in improving upper limb motor function and coordination with and without mental imagery training in chronic stroke...

Rawalpindi, Punjab Province, Pakistan
Recruiting
Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population
NCT06538974 · Phase: NA · Started 2023-02-16

In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990. It has been suggested that current rehabilitation frameworks (inp...

Paris, France
Recruiting
Efficacy of Treadmill Walking With Hidden Vision for Rehabilitation in the Subacute Phase of Stroke
NCT06972355 · Phase: NA · Started 2025-06-04

Objective: The aim of this study is to compare the efficiency of vision-obscured versus vision-retained treadmill gait training in subacute post-stroke patients. Methodology: Thirty-six patients with...

Metz, France
Recruiting
Effect of Kinesiology Taping and Swallowing Exercises on Suprahyoid Muscle Thickness and Swallowing Function in Stroke P
NCT06988215 · Phase: NA · Started 2025-03-04

This randomized controlled single-blind study aims to investigate the effect of kinesiology taping combined with resistance exercises on suprahyoid muscle thickness and swallowing function in patients...

Istanbul, bahçelievler, Turkey (Türkiye)
Recruiting
IVR ON UPPER-LIMB REHABILITATION IN STROKE PATIENTS: A CLINICAL TRIAL
NCT07609966 · Phase: NA · Started 2022-08-31

Stroke is the leading cause of acquired disability in adults. Neurorehabilitation aims to recover the affected function by stimulating neuroplasticity. Immersive virtual reality (IVR) has shown that i...

Girona, Spain
Recruiting
Cerebrolysin in Early Stroke Rehabilitation - Tertiary Study
NCT07043686 · Phase: NA · Started 2025-06-13

The study evaluates the effect and safety of Cerebrolysin administered during early rehabilitation in patients with moderate neurological impairment after acute ischemic stroke, conducted at the Depar...

Ljubljana, Slovenia
Recruiting
Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment
NCT07125170 · Phase: NA · Started 2025-08-06

This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient thera...

Independencia, Santiago Metropolitan, Chile
Recruiting
K01 Impacts of Lingual Endurance Exercise
NCT06072924 · Phase: NA · Started 2023-09-01

The goal of this clinical trial is to learn whether a tongue endurance exercise program can improve swallowing function in adults with dysphagia after a stroke. It also aims to explore how this exerci...

Cincinnati, Ohio, United States
Recruiting
The Effect of Mirror Therapy on Upper Extremity Motor Function in Stroke Rehabilitation
NCT06698380 · Phase: NA · Started 2024-11-18

The study aimed to determine the effect of mirror therapy versus conventional physical therapy treatment in improving upper extremity impairments and motor function among chronic hemiplegic subjects. ...

Riyadh, Riyadh Region, Saudi Arabia
Recruiting
Bilateral Robot-assisted Upper Extremity Rehabilitation on Motor Recovery in People With Subacute Stroke
NCT06906588 · Phase: NA · Started 2024-05-19

The goal of this clinical trial is to study the clinical effects of a robotic rehabilitation treatment through a bilateral exoskeleton (Bilateral Robot-Assisted Therapy-BRAT) during standard rehabilit...

Cassino, Italy, Italy · Rome, Italy, Italy · Sulmona, Italy, Italy
Recruiting
Peer Enriched Environment for Recovery (PEER)
NCT07463014 · Phase: NA · Started 2025-01-01

The goal of this interventional study is to assess whether a peer coaching intervention (PEER) can improve the well-being in individuals who experienced a stroke. The main questions it aims to answer ...

Singapore, Singapore
Recruiting
ExoDoF: Robotic Exoskeleton for Upper Limb Motor Rehabilitation After Stroke
NCT06496529 · Phase: NA · Started 2025-03-01

Two decades ago, the projection of recovery of the upper extremity (UE) after a stroke had a very poor prognosis worldwide. Nowadays, thanks to medical advances and early rehabilitation, the prognosis...

Santiago, Chile · Santiago, Chile · Santiago, Chile
Recruiting
Fall Risk Intervention for Stroke
NCT07349030 · Phase: NA · Started 2026-04-09

After stroke, falling is a common problem. Falls can lead to injury, as well as fear of future falls. It is important to try to prevent falls from happening after stroke. To goal of this study is to t...

Boston, Massachusetts, United States
Recruiting
Art Therapy and Its Effect on Non-Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery
NCT06713252 · Phase: NA · Started 2024-11-15

Stroke is one of the leading causes of disability and death worldwide, with the number of stroke patients steadily increasing due to the aging population. While traditional rehabilitation methods, suc...

Jiamusi, Heilongjiang, China
Recruiting
Perception of Advanced Rehabilitation Technologies Among Post-Stroke Patients and Rehabilitation Staff
NCT06986421 · Phase: Not specified · Started 2025-07-08

This observational study aims to assess the perception of advanced rehabilitation technologies among three key groups involved in stroke recovery: post-stroke patients, physicians specialized in Physi...

Hyères, France
Recruiting