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tDCS Treatment Clinical Trials

229 actively recruiting studies

Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter
NCT07354139 · Phase: NA · Started 2026-03-17

The goal of this study is to find out whether a type of noninvasive brain stimulation can help reduce speech errors, such as repetitions, blocks, and prolongations, in people who stutter. This pilot s...

Richardson, Texas, United States
Recruiting
Personalized High-Definition tDCS Protocols for Chronic Pain Treatment
NCT07432841 · Phase: NA · Started 2025-04-03

This study aims to examine the use of neurostimulation as a potential adjuvant treatment for chronic pain. Among neurostimulation techniques, transcranial direct current stimulation (tDCS) represents ...

Milan, Italy · Palermo, Italy · Palermo, Italy
Recruiting
Combined Effects of Green Light and Transcranial Direct Current Stimulation in Migraine Patients.
NCT06943625 · Phase: NA · Started 2025-04-24

According to the Global Burden of Disease (GBD) study, headache disorders are among the most prevalent and disabling conditions worldwide, with estimated 1-year prevalence of migraine (22.5%) in Pakis...

Rawalpindi, Punjab Province, Pakistan · Rawalpindi, Punjab Province, Pakistan
Recruiting
tDCS: Sleep to Mood in Depression (S2M-D)
NCT07572526 · Phase: NA · Started 2026-06-04

The purpose of this study is to determine whether changes in sleep consolidation occur during home-based transcranial direct current stimulation (tDCS) in adults with moderate depression and whether t...

New York, New York, United States
Recruiting
WHITBY: Working Towards Better Healthcare Interventions for Tinnitus: a Brain Stimulation studY
NCT06628414 · Phase: NA · Started 2024-12-01

Tinnitus - the awareness of sound without any outside source - affects around 15% of people and can cause anxiety and depression. Treatment options are limited and do not address tinnitus directly (e....

Nottingham, United Kingdom
Recruiting
Exploring the Possible Beneficial Impact of Non-invasive and Invasive Neuromodulation on Freezing of Gait in Parkinson's
NCT06505460 · Phase: NA · Started 2024-04-30

Freezing of gait (FOG) stands out as a devastating symptom of Parkinson's disease (PD), where patients may become momentarily glued to the ground, rendering them incapable of walking efficiently. The ...

Taichung, Taiwan
Recruiting
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
NCT06974773 · Phase: NA · Started 2025-12-04

The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis. The study also ai...

San Francisco, California, United States
Recruiting
Comparison of Two Non-invasive Neuromodulation Techniques as Synergistic Therapy to Cognitive Stimulation in Amnestic Mi
NCT06467253 · Phase: NA · Started 2023-06-01

This is a comparative, double-blind, randomized controlled clinical trial for people with Amnestic Mild Cognitive Impairment. The investigators will compare the effects of two non-invasive neuromodula...

Mexico City, Mexico
Recruiting
Use of Transcranial Direct Current Stimulation (TDCS) in an Active Pain Coping Program for Patients With Fibromyalgia: A
NCT07239427 · Phase: NA · Started 2025-12-01

The trial is designed to determine the added effect of active transcranial direct current stimulation (tDCS) when combined with a multimodal Active Pain Coping Program in individuals with fibromyalgia...

Valladolid, Valladolid, Spain
Recruiting
Treatment Outcomes With tDCS in Post-Stroke Aphasia
NCT03929432 · Phase: NA · Started 2019-09-03

The purpose this study is to test the utility of pairing external neuromodulation with behavioral language treatment to boost therapy outcomes and to investigate the mechanisms associated with recover...

Little Rock, Arkansas, United States
Recruiting
Neuromodulation and Cognitive Training in Opioid Use Disorder
NCT03773523 · Phase: NA · Started 2019-08-01

The relapsing nature of opioid use disorder is a major obstacle to successful treatment. About 90% of those entering treatment will relapse within one year. To improve treatment outcome, new intervent...

Minneapolis, Minnesota, United States
Recruiting
Home-Based tDCS for Depression in BPD
NCT06972368 · Phase: NA · Started 2026-01-01

The present study aims to assess the feasibility of home-based tDCS in remote and urban areas (primary objective). The secondary aim is to obtain a preliminary assessment of the efficacy of 14 home-b...

Montreal, Quebec, Canada
Recruiting
tDCS for Social Media Addiction
NCT07410104 · Phase: NA · Started 2026-03

The goal of this clinical trial is to learn whether transcranial direct current stimulation (tDCS), a non-invasive brain stimulation, can reduce "craving" and problematic levels of social media/intern...

Almada, Portugal
Recruiting
Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury
NCT05762796 · Phase: NA · Started 2024-02-20

Mild traumatic brain injury (mTBI) often causes persistent motor and cognitive deficits in children resulting in functional limitations. We are testing a brain stimulation method along with evaluating...

Buffalo, New York, United States
Recruiting
Transcranial Direct Current Stimulation for Post Treatment Lyme Disease
NCT06915324 · Phase: NA · Started 2025-07-14

The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme ...

San Francisco, California, United States · New York, New York, United States
Recruiting
GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy
NCT06747676 · Phase: PHASE1, PHASE2 · Started 2025-01-03

We aim to determine if targeted high-definition transcranial direct current stimulation (HD-tDCS) can safely correct errors in visual verticality perception in patients after stroke affecting either h...

Ribeirão Preto, São Paulo, Brazil · Ribeirão Preto, São Paulo, Brazil
Recruiting
Remotely-supervised Neuromodulation in PPA
NCT07260253 · Phase: NA · Started 2026-04-15

The goal of this clinical trial is to learn whether home-based brain stimulation combined with virtual speech-language therapy can improve communication abilities in adults with logopenic variant prim...

San Francisco, California, United States · Austin, Texas, United States
Recruiting
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
NCT07334977 · Phase: PHASE2 · Started 2024-12-11

The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate e...

Bordeaux, France · Bruges, France
Recruiting
Reboot Pain (tDCS)
NCT07411859 · Phase: NA · Started 2026-02-16

This study will examine the effectiveness of tDCS (Transcranial Direct Current Stimulation) in reducing chronic pain when used with Emory Healthcare Veterans Program (EHVP)-ABHP (Accelerated Behaviora...

Atlanta, Georgia, United States
Recruiting
tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity
NCT05225233 · Phase: NA · Started 2022-11-23

The purpose of this study is to investigate if transcranial direct current stimulation (tDCS) can increase the effectiveness of cognitive training to reduce impulsivity in individuals with obesity, an...

Minneapolis, Minnesota, United States
Recruiting
Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder
NCT07318480 · Phase: NA · Started 2026-02-25

The researchers will test whether cognitively enhanced transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex can reduce craving in inpatients with cocaine use disorder. ...

New York, New York, United States
Recruiting
The Effect of Transcranial Direct Current Stimulation (tDCS) in Improving Emotion Health
NCT07319143 · Phase: NA · Started 2026-01-08

The goal of this clinical trial is to investigate how transcranial direct current stimulation (tDCS) affects emotion functions in young adults aged 18-35 from the local community, including both male ...

Hong Kong, Hong Kong
Recruiting
Effects of a Neurorehabilitation Program Based on CIMT and Non-invasive Neuromodulation Through C-tDCS on the Recovery o
NCT07619703 · Phase: NA · Started 2026-03-01

General Objective To determine the effects of a neurorehabilitation program based on Constraint-Induced Movement Therapy (CIMT) and non-invasive neuromodulation through cerebellar transcranial direct ...

Temuco, Araucania, Chile
Recruiting
Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)
NCT06901687 · Phase: PHASE2 · Started 2025-08-11

This project is a double-blind, sham-controlled, parallel-arm, randomized controlled trial. We will recruit n=170 people living with MS, who are experiencing an episode of depression in the context of...

New York, New York, United States
Recruiting
Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTS
NCT07116109 · Phase: NA · Started 2025-07-01

The purpose of this study is to examine comparative effectiveness of two home-based telemedicine delivered interventions: transcranial Direct Current Stimulation (tDCS) combined with Massed Prolonged ...

Charleston, South Carolina, United States · Houston, Texas, United States
Recruiting
Stuttering and Neuromodulation
NCT07222163 · Phase: NA · Started 2025-09-04

The purpose of this study is to collect preliminary data on the efficacy of transcranial direct current stimulation (tDCS) combined with traditional behavioral techniques to reduce stuttering severity...

New York, New York, United States
Recruiting
Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
NCT06413173 · Phase: NA · Started 2024-07-25

The proposed study will evaluate a new approach to cognitive rehabilitation of mTBI using a brain stimulation technique called "Remotely Supervised Transcranial Direct Current Stimulation combined wit...

San Diego, California, United States · Minneapolis, Minnesota, United States
Recruiting
Neuromodulation and Cognitive Training for Substance Use Disorders
NCT04426214 · Phase: NA · Started 2021-07-16

The relapsing nature of substance use disorder is a major obstacle to successful treatment. About 70% of those entering treatment will relapse within one year. To improve treatment outcome, new interv...

Minneapolis, Minnesota, United States
Recruiting
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
NCT04296604 · Phase: NA · Started 2014-09

In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have d...

Boston, Massachusetts, United States
Recruiting
RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative
NCT07184983 · Phase: NA · Started 2025-11-12

The purpose of this sham-controlled pilot randomized controlled trial (RCT) is to evaluate the feasibility, safety, and preliminary efficacy of a one-month intervention consisting of 20 home-based act...

New York, New York, United States
Recruiting
Effect of Transcranial Direct Current Stimulation on Risk of Falling in Cerebral Palsy Spastic Hemiplegic Children
NCT06730763 · Phase: NA · Started 2024-12-01

The purpose of this study was to determine: * If there is an effect of transcranial direct current stimulation in improvement the functional balance in CP spastic hemiplegic children. * If there are ...

Giza, Giza Governorate, Egypt
Recruiting
Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome
NCT04206215 · Phase: NA · Started 2021-04-16

The purpose of this study is to assess the effects of tDCS in combination with TUS for the treatment of pain in subjects with Carpal Tunnel Syndrome. The investigators hypothesize that there will be a...

Charlestown, Massachusetts, United States
Recruiting
Combining fMRI and tDCS in Neuropathic Pain
NCT06237075 · Phase: NA · Started 2023-09-11

The proposed project aims to explore possible neuromodulatory effects of transcranial direct current stimulation (tDCS) on neuropathic pain caused by peripheral neuropathy. tDCS will be performed thro...

Taipei, Taiwan
Recruiting
Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease
NCT06843252 · Phase: NA · Started 2025-09-02

The researchers hope to find out effects of transcranial direct current stimulation (tDCS) sessions on the behavioral symptoms of Huntington's Disease. If participants are eligible to continue, they w...

San Antonio, Texas, United States
Recruiting
Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic
NCT06334952 · Phase: NA · Started 2024-12-18

The goal of this clinical trial is to to obtain a significant decrease in seizure frequency in patients with refractory focal epilepsy after applying treatment of cathodal tDCS, compared to sham stimu...

Bordeaux, France · Bron, France · Lille, France
Recruiting
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
NCT05972200 · Phase: NA · Started 2023-09-01

The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial...

Roma, Italy
Recruiting
Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With
NCT06838013 · Phase: NA · Started 2024-06-17

This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task...

Hong Kong, Hong Kong
Recruiting
Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
NCT05706831 · Phase: NA · Started 2022-09-01

The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are: * to evalua...

Bari, Ba, Italy
Recruiting
Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using Combined P
NCT05874258 · Phase: NA · Started 2023-05-15

Glaucoma is a complex disease that can result in progressive vision loss. It is the second leading cause of blindness, accounting for 23% of permanent blindness in Hong Kong. There are no treatments t...

Hong Kong, Hong Kong
Recruiting
Exploring the Role of the Prefrontal Cortex in Decision-Making
NCT07080489 · Phase: NA · Started 2025-03-04

The goal of this study is to examine whether high-definition transcranial direct current stimulation (HD-tDCS) can influence decision-making for emotionally valenced content in younger and older adult...

Bern, Switzerland
Recruiting
Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy (VRMT) and Transcranial Direct Current Stim
NCT06764797 · Phase: PHASE3 · Started 2023-09-19

This study will investigate whether combining virtual reality-based mirror therapy (VRMT) and transcranial direct current stimulation (tDCS) alongside conventional physical therapy (CPT) will signific...

Riyadh, Riyadh Region, Saudi Arabia · Riyadh, Riyadh Region, Saudi Arabia
Recruiting
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
NCT05638464 · Phase: NA · Started 2021-08-13

A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only on...

Hong Kong, Hong Kong
Recruiting
Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury
NCT06848140 · Phase: NA · Started 2025-10-01

The purpose of this study is to learn more about how brain stimulation affects word finding problems in people who have a traumatic brain injury (TBI). The type of brain stimulation used is called tra...

Boston, Massachusetts, United States
Recruiting
Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke
NCT06818240 · Phase: NA · Started 2024-11-01

Stroke often impairs lower limb control, resulting in gait abnormalities and difficulties in dual-task performance, such as walking while engaging in cognitive activities. This study examines the effe...

Hong Kong, China, Hong Kong
Recruiting
Learning Study: Improving Vision in Adults With Macular Degeneration
NCT04762368 · Phase: NA · Started 2021-02-13

The purpose of this study is to test whether a kind of brain stimulation called anodal transcranial direct current stimulation (a-tDCS) can be combined with perceptual learning to improve the ability ...

Waterloo, Ontario, Canada · Hung Hom, Kowloon, Hong Kong
Recruiting
Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke
NCT06440707 · Phase: PHASE2 · Started 2025-07-15

Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), a...

Los Angeles, California, United States · Baltimore, Maryland, United States · Durham, North Carolina, United States
Recruiting
Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia
NCT07151677 · Phase: NA · Started 2025-08-04

The goal of this clinical trial is to determine if electrical brain stimulation applied to the front parts of the brain can help people who have had a stroke improve their fatigue, language, and atten...

Ann Arbor, Michigan, United States · Syracuse, New York, United States
Recruiting
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
NCT04142866 · Phase: NA · Started 2025-01-03

The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investiga...

New York, New York, United States
Recruiting
Multifocal HD-tDCS and Motor Function
NCT06561165 · Phase: NA · Started 2025-02-25

The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (H...

Ann Arbor, Michigan, United States
Recruiting
Remote Stimulation and Training to Advance Recovery From TBI in Seniors
NCT07332299 · Phase: NA · Started 2026-01-15

The goal of this clinical trial is to learn if combining brain stimulation with cognitive training can improve thinking skills in older adults who have had a traumatic brain injury (TBI). The main qu...

Minneapolis, Minnesota, United States
Recruiting
Effect of Multisite High-definition Transcranial Direct Current Stimulation Targeting Sensorimotor Network
NCT06648954 · Phase: NA · Started 2022-08-13

Transcranial direct current stimulation (tDCS) has been applied to facilitate cortical excitability in stroke populations, as increasing evidence suggests that clinical recovery from stroke is attribu...

Hong Kong, Hong Kong
Recruiting
Improving Visual Field Deficits With Noninvasive Brain Stimulation
NCT05085210 · Phase: NA · Started 2022-01-25

This is a randomized, pilot interventional study in participants with visual field deficit (VFD) caused by cortical lesion. Damage to the primary visual cortex (V1) causes a contra-lesional, homonymou...

Boston, Massachusetts, United States
Recruiting
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
NCT05866003 · Phase: NA · Started 2023-07-01

After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a pe...

Cleveland, Ohio, United States
Recruiting
HD-tDCS to Modulate Connectivity
NCT05959551 · Phase: NA · Started 2023-07-01

The purpose of the proposed study is to broaden our understanding on the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) so that its clinical effects can be further...

Winnipeg, Manitoba, Canada
Recruiting
Brain Research and Integrative Neuroscience Network for COVID-19
NCT06517706 · Phase: NA · Started 2024-11-15

The aim of the experimental study is to investigate two interventions for the management of cognitive symptoms resulting from long COVID. Participants will be randomly assigned into two interventions....

Nicosia, Cyprus, Cyprus
Recruiting
Efficacy of Cerebello-spinal Direct Current Stimulation (csDCS) on Functional Mobility in Chronic Stroke Patients
NCT07073287 · Phase: PHASE2 · Started 2024-05-01

The aim of this clinical trial is to determine if cerebello-spinal direct current stimulation (csDCS) is effective in treating gait disorders in individuals with chronic stroke. Additionally, the tria...

João Pessoa, Paraíba, Brazil · Recife, Pernambuco, Brazil · Rio de Janeiro, Rio de Janeiro, Brazil
Recruiting
Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways
NCT07469384 · Phase: NA · Started 2026-02-01

This study investigates the ability of transcranial direct current stimulation (tDCS) applied over the motion processing area of the brain (area MT) to improve face emotion recognition (FER) ability. ...

Orangeburg, New York, United States
Recruiting
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
NCT04897334 · Phase: NA · Started 2021-09-21

The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve c...

Philadelphia, Pennsylvania, United States
Recruiting
Evaluating tDCS Brain-stimulation in Depression Using MRI
NCT05598034 · Phase: NA · Started 2022-10-20

Patients, physicians, and those who fund depression research are keenly interested in depression treatments that do not involve taking medications. One promising candidate treatment is transcranial di...

Los Angeles, California, United States
Recruiting
TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
NCT06294184 · Phase: NA · Started 2023-11-01

The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individu...

Guangzhou, Guangdong, China
Recruiting
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
NCT07524400 · Phase: NA · Started 2026-05-10

A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct c...

Fuenlabrada, Madrid, Spain
Recruiting
Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI)
NCT06378463 · Phase: NA · Started 2024-05-06

Seven per cent of patients suffering from severe mental illness (SMI) need long-term intensive treatment and support in a clinical setting or sheltered living. These service users often experience pro...

Assen, Drenthe, Netherlands · Zuidlaren, Drenthe, Netherlands · Leeuwarden, Provincie Friesland, Netherlands
Recruiting
tDCS and Spasticity in Stroke Patients
NCT06598683 · Phase: NA · Started 2024-10-01

Multiple research has worked on tDCS and its impact on stroke. But none have studied the effects of tDCS on stroke in relation to the different stages of stroke like mild, moderate, moderate to severe...

Rawalpindi, Punjab Province, Pakistan · Rawalpindi, Punjab Province, Pakistan
Recruiting
Direct Transcranial Electrical Stimulation in Tobacco Addiction (tDCS)
NCT04209153 · Phase: Not specified · Started 2021-11-29

In summary, there are currently many therapeutic tools for achieving some degree of control or even cessation of tobacco addictive use. No single therapy seems to have proven itself sufficiently effec...

Paris, IDF, France
Recruiting
Brain Stimulation Combined With Watching Hand Movements to Improve Hand Recovery in Chronic Stroke
NCT07400939 · Phase: NA · Started 2026-04-01

This study investigates the neurophysiological mechanisms underlying the combined use of transcranial direct current stimulation (tDCS) and action observation therapy (AOT) for hand motor recovery in ...

Kota Kinabalu, Sabah, Malaysia · Kota Kinabalu, Sabah, Malaysia
Recruiting
Patient-tailored Transcranial Direct Current Stimulation to Improve Stroke Rehabilitation
NCT05355831 · Phase: NA · Started 2022-08-28

In a double-blinded sham-controlled study the effect of patient-tailored transcranial direct current stimulation during rehabilitation training will be examined....

Copenhagen, Denmark · Herlev, Denmark · Hvidovre, Denmark
Recruiting
Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Si
NCT07385508 · Phase: Not specified · Started 2026-01-16

Disorders of consciousness (DOC), such as the vegetative state/unresponsive wakefulness syndrome (VS/UWS) and the minimally conscious state (MCS), represent severe clinical conditions arising from acq...

Messina, Sicily, Italy
Recruiting
Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Gait and Balance in Parkinson's Disea
NCT07381907 · Phase: NA · Started 2025-06-09

Parkinson's disease can cause slow or unsteady walking and balance problems that raise the risk of falls. This study will test whether adding a gentle, non-invasive brain stimulation called transcrani...

Belém, Pará, Brazil
Recruiting
A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia
NCT06668610 · Phase: NA · Started 2024-10-01

The goal of this clinical trial is to learn if an integrated protocol using multifocal non invasive brain stimulation and brain recording combined with cognitive training is effective in treating cogn...

Caserta, Italy, Italy
Recruiting
Effects of Transcranial Direct Current Stimulation (tDCS) on Inhibition and Brain Function in Primary Progressive Aphasi
NCT06473714 · Phase: NA · Started 2024-11-04

Primary progressive aphasia (PPA) is a focal dementia characterized by primary impairment of language abilities and functional disturbances associated with language. Although PPA is a progressive dis...

Nice, France
Recruiting
Use of TDCS Stimulation in Neurological and Gynaecological Conditions
NCT06891690 · Phase: NA · Started 2025-02-05

The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients. And the impact of tDCS stimulati...

Poznan, Poland
Recruiting
Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke
NCT05479006 · Phase: NA · Started 2022-09-30

Significant motor impairments occur in 80% of individuals after moderate to severe stroke and impact the body side to the lesioned hemisphere. Typical motor impairments involve loss of dexterity with ...

Urbana, Illinois, United States
Recruiting
tDCS as Treatment for Motor Function
NCT07291687 · Phase: NA · Started 2025-10-30

Previous preliminary results are sufficiently impressive to suggest that tDCS stimulation does have the potential to improve motor function when that ability is trained during stimulation. In the prop...

Toronto, Ontario, Canada
Recruiting
The Use of tDCS for Vaping Reduction
NCT06885606 · Phase: NA · Started 2026-01-01

Project Summary - tDCS for Vaping Reduction Background: While the prevalence of tobacco smoking has plateaued over the last several years, the prevalence of nicotine vaping (e-cigarettes) continues t...

Toronto, Ontario, Canada
Recruiting
Effects of tDCS Combined With CBI on Postsurgical Pain
NCT04199780 · Phase: NA · Started 2021-01-11

The purpose of this study is to determine whether a new medical technology can help reduce post-operative total knee or hip pain when combined with a Cognitive-Behavioral intervention (CBI). This new...

Charleston, South Carolina, United States
Recruiting
tDCS and Bimanual Therapy for Children With Hemiplegic Cerebral Palsy
NCT03402854 · Phase: NA · Started 2019-12-01

The goal of this study is to test the efficacy of transcranial direct current stimulation combined with bimanual training on hand function in children with unilateral spastic cerebral palsy (USCP). Ch...

White Plains, New York, United States
Recruiting
Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Const
NCT06786000 · Phase: NA · Started 2023-04-11

This clinical trial aims to evaluate the effect of different types of tDCS modulation with mCIMT in improving affected upper-limb motor function for stroke patients. The main question it seeks to answ...

Riyadh, Riyadh Region, Saudi Arabia
Recruiting
tDCS and Cognitive Training for Restrictive Eating Disorders
NCT06624150 · Phase: PHASE1 · Started 2024-08-02

This study looks at adults with restrictive eating disorders who are currently receiving outpatient treatment for their eating disorder to examine whether a new brain stimulation technique called non-...

Minneapolis, Minnesota, United States
Recruiting
Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation
NCT04869059 · Phase: NA · Started 2021-08-01

The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought ...

Dallas, Texas, United States
Recruiting
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
NCT06286800 · Phase: NA · Started 2024-12-18

The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustai...

Houston, Texas, United States
Recruiting
tDCS for Post-Stroke Cognitive Impairment
NCT06516588 · Phase: PHASE2 · Started 2024-09-30

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in participants with post-stroke cognitive impairment (PSCI)....

Oklahoma City, Oklahoma, United States
Recruiting
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
NCT05661084 · Phase: NA · Started 2023-01-24

This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cogni...

Boston, Massachusetts, United States
Recruiting
Use of Anodal tDCS to Enhance Upper Limb Recovery in Stroke
NCT07151729 · Phase: NA · Started 2025-09-01

This will be a randomized, blinded, sham-controlled trial. The medical device used, Soterix Medical 1x1 tDCS stimulator, is capable of delivering either real or sham tDCS and has been used in many ran...

Singapore, Singapore, Singapore
Recruiting
High Definition Transcranial Direct Current Stimulation of Right Inferior Frontal Gyrus to Improve Social Impairments in
NCT06723522 · Phase: NA · Started 2024-08-30

The goal of this clinical trial is to learn if high definition transcranial direct current stimulation (HD-tDCS) of right inferior frontal gyrus works to improve social impairments in children with au...

Changsha, Hunan, China
Recruiting
Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)
NCT06455527 · Phase: NA · Started 2025-01-02

This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate de...

New York, New York, United States
Recruiting
Home-Based tDCS Treatment Of Major Depressive Disorder
NCT06976697 · Phase: NA · Started 2025-06-27

The REACH-tDCS study will evaluate the safety and efficacy of a noninvasive, at-home self-administered Sooma tDCS brain stimulation treatment for Major Depressive Disorder. The study uses randomized, ...

Boston, Massachusetts, United States
Recruiting
Improving Measurement and Treatment of Post-stroke Neglect
NCT03317860 · Phase: NA · Started 2018-07-02

This study examines how to best assess and treat post-stroke neglect. This study will examine the preliminary effects of an innovative intervention (repetitive task-specific practice + transcranial di...

Pittsburgh, Pennsylvania, United States
Recruiting
Multimodal Investigation of Neural Plasticity
NCT06453980 · Phase: NA · Started 2024-05-13

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognit...

Ann Arbor, Michigan, United States
Recruiting
Optimized and Personalized Trans-cranial Brain Stimulation in Partial Refractory Epilepsies
NCT06212609 · Phase: NA · Started 2023-12-01

Epilepsy is one of the most common neurological diseases, affecting between 0.5% and 1% of the general population. Therefore, new diagnostic and treatment methods are having a big impact on society. E...

Amiens, France
Recruiting
Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency
NCT05877560 · Phase: NA · Started 2025-03-01

The goal of this randomized controlled trial is to test the effectiveness of non-invasive brain stimulation in treating adults with symptomatic convergence insufficiency compared to vergence/accommoda...

Downers Grove, Illinois, United States
Recruiting
Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Dise
NCT05326451 · Phase: NA · Started 2023-06-21

The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle st...

Houston, Texas, United States
Recruiting
A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
NCT05998031 · Phase: NA · Started 2024-04-24

The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compa...

Gainesville, Florida, United States
Recruiting
Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms
NCT06801639 · Phase: NA · Started 2025-07-15

Participants will be asked to participate in this research study of a device that creates transcranial direct current stimulation (tDCS). The researchers hope to learn if 30 minute sessions of transc...

San Antonio, Texas, United States
Recruiting
Transcranial Stimulation for Physiotherapy Optimisation - Chronic Low Back Pain (STOP-CLBP)
NCT05757609 · Phase: NA · Started 2023-08-21

The main objective of this study is to investigate the effects of non-invasive brain stimulation (the so-called transcranial direct current stimulation ; tDCS) combined with an active physiotherapy pr...

Geneva, Switzerland
Recruiting
The Added Value of Transcranial Direct Current Stimulation (tDCS) During Exercise for People With Chronic Widespread Pai
NCT07212829 · Phase: NA · Started 2026-02-01

Many people with chronic widespread pain (CWP) feel more pain and fatigue after exercise. This makes it hard to stay active. Unfortunately, the investigators do not fully understand why this happens a...

Jette, Belgium
Recruiting
Longitudinal Study Examining At-Home tDCS
NCT04524338 · Phase: NA · Started 2021-02-22

Participants with dementia have reported improvements after receiving tDCS in a study at our lab. Although we make an effort to enroll such participants in further tDCS research studies, some particip...

Montreal, Quebec, Canada
Recruiting
Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)
NCT05079464 · Phase: NA · Started 2021-11-22

People with vascular conditions are at risk of having memory problems, and these memory problems increase the risk for further cognitive decline. Brain stimulation has been used to improve mood and me...

Toronto, Ontario, Canada
Recruiting
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy
NCT06241963 · Phase: NA · Started 2024-02-12

To observe the clinical effect and safety of transcranial electrical stimulation on patients with refractory epilepsy before and after treatment and analyze its therapeutic mechanism....

Hefei, Anhui, China
Recruiting
Long Term Effect of Brain Stimulation in PPA
NCT07158216 · Phase: NA · Started 2025-09-15

The goal of this clinical trial is to investigate the effect of non-invasive brain stimulation techniques in the progression of primary progressive aphasia for 6 months. We will compare three modaliti...

Madrid, Spain
Recruiting
Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME)
NCT07228468 · Phase: NA · Started 2025-11-18

Depression is a prevalent and debilitating disorder. The most common treatments are antidepressant medications and talking therapies. However, for many individuals, these are not their treatment of ch...

Cardiff, United Kingdom · London, United Kingdom · Newcastle, United Kingdom
Recruiting
Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD
NCT06883266 · Phase: NA · Started 2024-11-11

The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left primary motor cortex (M1) will induce long-lasting effects in improving motor function and reducing motor fatigue and f...

Fargo, North Dakota, United States
Recruiting
Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation
NCT03857529 · Phase: NA · Started 2019-08-01

This pilot study for stroke patients with chronic upper limb hemiplegia will examine the effects of non-invasive brain stimulation and neuromuscular electrical stimulation on hand motor control and co...

Cleveland, Ohio, United States
Recruiting
The Effects of Specific tDCS on Cognition in MCI
NCT05919485 · Phase: NA · Started 2023-08-01

INTRODUCTION: Mild cognitive impairment (MCI) is a critical transitional stage in dementia related disorders. Dorsolateral prefrontal cortex (DLPFC), and the lateral parietal (LPC) cortex are subject...

Antalya, Alanya, Turkey (Türkiye)
Recruiting
Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients
NCT07303998 · Phase: NA · Started 2025-03-04

This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and onlin...

Tucson, Arizona, United States
Recruiting
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
NCT06821568 · Phase: NA · Started 2025-09-02

The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cor...

Roslindale, Massachusetts, United States · Tel Aviv, Israel
Recruiting
Enhancing Language Function in Primary Progressive Aphasia
NCT04920318 · Phase: NA · Started 2021-08-30

This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine beha...

Tucson, Arizona, United States
Recruiting
Effect of Transcranial Direct Current Stimulation in Altered States of Consciousness
NCT06236503 · Phase: NA · Started 2023-01-10

Transcranial Direct Current Stimulation (tDCS) is a non-invasive, painless brain stimulation treatment that uses low-intensity direct electrical currents to stimulate specific parts of the brain. Tran...

Messina, Italia, Italy
Recruiting
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
NCT05386394 · Phase: PHASE2 · Started 2024-02-13

While many have strongly suggested that transcranial direct current stimulation (tDCS) may represent a beneficial intervention for patients with primary progressive aphasia (PPA), this promising techn...

Baltimore, Maryland, United States · Philadelphia, Pennsylvania, United States · Toronto, Ontario, Canada
Recruiting
Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training and Decision-making
NCT03886025 · Phase: NA · Started 2022-09-15

This study aims to (i) assess the effects of combined tDCS and cognitive training on decision-making on a trained task (Iowa Gambling Task; IGT); and (ii) test generalization to a closely related cogn...

Kingston, Ontario, Canada
Recruiting
tDCS Effect on Psychotic Symptoms in Dementia With Lewy Bodies (DLB), and Impacts on Caregiver Burden
NCT06785948 · Phase: NA · Started 2025-01-10

The goal of this pilot prospective study is to evaluate the effect of tDCS on psychotic-like symptoms in patients with Lewy Body Dementia (LBD). The main questions it aims to answer are: * What is th...

Monaco, Monaco
Recruiting
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
NCT00739362 · Phase: PHASE2 · Started 2009-01-19

This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affe...

Phoenix, Arizona, United States
Recruiting
Study of Transcranial Direct Current Stimulation to Treat Epilepsy
NCT05673915 · Phase: NA · Started 2023-04-12

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic sei...

Rochester, Minnesota, United States
Recruiting
Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
NCT05437159 · Phase: NA · Started 2023-04-03

Persistent developmental stuttering affects more than three million people in the United States, and it can have profound adverse effects on quality of life. Despite its prevalence and negative impact...

Boston, Massachusetts, United States · Boston, Massachusetts, United States · Ann Arbor, Michigan, United States
Recruiting
tDCS Plus Varenicline for Smoking Cessation
NCT06798324 · Phase: PHASE4 · Started 2025-03-10

The goal of this clinical trial is to determine if active transcranial direct current stimulation (tDCS) plus varenicline is an effective, safe and accessible treatment option for smoking cessation. T...

Toronto, Ontario, Canada
Recruiting
Home-based Transcranial Direct Current Stimulation (tDCS) to Promote Social Communication and Behaviour in Children With
NCT06129058 · Phase: PHASE2 · Started 2023-10-20

Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that can be delivered in a home setting. It is a safe and tolerable intervention that has shown promise for i...

Toronto, Ontario, Canada
Recruiting
Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue
NCT06810817 · Phase: NA · Started 2024-10-28

This study aims to evaluate the effect of transcranial direct current stimulation and cognitive behavioural programme on fatigue and its related outcomes among people with stroke....

Hong Kong, Hong Kong
Recruiting
A Study of Home-use Brain Stimulation to Treat Bipolar Depression
NCT07556692 · Phase: NA · Started 2026-04-24

Bipolar depression is a long-lasting and disabling condition, and many people continue to experience depressive symptoms despite standard treatments. Transcranial direct current stimulation (tDCS) is ...

London, United Kingdom
Recruiting
tDCS of the Left dlPFC: Effects on Information Processing
NCT07168031 · Phase: NA · Started 2025-08-06

This study investigates how a non-invasive form of brain stimulation, called transcranial direct current stimulation (tDCS), affects brain activity and information processing in younger and older adul...

Bern, Switzerland
Recruiting
Trial of Enhanced Neurostimulation for Anorexia
NCT05788042 · Phase: NA · Started 2023-08-02

Preliminary open-label studies have suggested that non-invasive brain stimulation methods of both transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS)...

Sydney, New South Wales, Australia
Recruiting
Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Var
NCT03887481 · Phase: NA · Started 2022-10-15

AD afflicts over 5.5. million Americans and is one of the most expensive diseases worldwide. In AD the variant in which language functions are most affected are referred to as 'logopenic variant Prima...

Baltimore, Maryland, United States
Recruiting
Effects of tDCS for Enhancing Cognitive Function in Individuals With Persistent Post-Concussion Syndrome
NCT06376500 · Phase: NA · Started 2025-09-01

Globally, 10 million new traumatic brain injury (TBI) cases are estimated annually, with mild traumatic brain injury (mTBI) accounting for 75-90% of all TBI cases. It is estimated that 40-80% of indiv...

Hung Hom, Kowloon, Hong Kong
Recruiting
tDCS on Parkinson's Disease Cognition
NCT03025334 · Phase: NA · Started 2017-03-22

Parkinson's disease (PD) has been classically regarded as a "movement disorder", so earlier work has focused on treating motor symptoms only. As PD patients now have longer life expectancy, the relati...

Winnipeg, Manitoba, Canada
Recruiting
Non-Invasive Brain Stimulation to Improve Language in Down Syndrome.
NCT07044804 · Phase: NA · Started 2025-01-27

Down syndrome (DS) is associated with cognitive deficits, caused by alterations in neuroplasticity and synaptic transmission. Non-invasive brain stimulation techniques, such as transcranial direct cur...

Rome, Italy, Italy
Recruiting
Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Uppe
NCT07288385 · Phase: NA · Started 2025-12-28

Following a stroke, the function of the distal upper limb, especially hand and finger movements, is often severely compromised, significantly restricting the ability to carry out daily activities. It ...

Riyadh, Saudi Arabia
Recruiting
The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia
NCT04033679 · Phase: NA · Started 2019-08-15

This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication ad...

Toronto, Ontario, Canada
Recruiting
Network Properties As Biomarkers for Non-Invasive Brain Stimulation (NIBS) After Stroke
NCT05560724 · Phase: NA · Started 2022-07-01

The present study will evaluate the potential of cortico-cerebellar network properties derived from neuroimaging in a group of chronic stroke patients to explain inter-subject variability in responsiv...

Hamburg, Free and Hanseatic City of Hamburg, Germany
Recruiting
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia
NCT04267003 · Phase: NA · Started 2020-01-09

People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance. Unfortunately, even our best trea...

Sacramento, California, United States
Recruiting
Investigating the Effects of Transcranial Direct Current Stimulation to Different Brain Regions on Ankle Tracking Motor
NCT06556043 · Phase: NA · Started 2024-07-09

Ankle control is essential to safe over-ground navigation for humans. Middle- aged and older adults and patients with stroke whose ankle control is poor often lose their balance or fall. Transcranial ...

Taipei, Taiwan
Recruiting
Accelerated High-Dose tDCS for Depression
NCT07226011 · Phase: NA · Started 2025-12-15

In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with d...

Charleston, South Carolina, United States
Recruiting
Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia
NCT06760910 · Phase: NA · Started 2021-01-30

As a neurodevelopmental visual disorder, amblyopia, especially monocular form-deprivation amblyopia, can lead to severe visual developmental impairments. Due to reduced neural plasticity in the visual...

Tianjin, Tianjin Municipality, China
Recruiting
Understanding How Alzheimer's Disease Impacts the Therapeutic Response to Transcranial Direct Current Stimulation
NCT05508841 · Phase: NA · Started 2022-09-01

There is currently little symptomatic therapy for Alzheimer's Disease (AD) and nothing effective for individuals with Frontotemporal dementia (FTD). However, neuromodulation with transcranial direct c...

Toronto, Ontario, Canada
Recruiting
Combined taVNS and tDCS in Subacute Stroke Patients
NCT06244914 · Phase: NA · Started 2024-02-15

Ischemic stroke, the most prevalent neurological disorder, is treated with medication and thrombectomy but with limited success, especially in chronic stages where traditional rehabilitation is the pr...

Tainan, Tainan, Taiwan
Recruiting
At-Home tDCS as Maintenance Therapy
NCT07269964 · Phase: NA · Started 2024-10-01

The primary purpuse of this pilot study is to find out whether a home-based transcranial direct current stimulation (tDCS) program is feasible and well tolerated as maintenance therapy and whether the...

München, Bavaria, Germany · München, Germany
Recruiting
Non-invasive Brain Stimulation in Multiple Sclerosis Fatigue
NCT07438964 · Phase: NA · Started 2026-03-02

The neurobiological basis of central fatigue in multiple sclerosis remained unclear so far. This study investigates reward-related brain mechanisms, inflammation, and their modulation by non-invasive ...

Berlin, State of Berlin, Germany
Recruiting
Low Voltage Electrical Stimulation for Depression in Parkinson's Patients
NCT06467695 · Phase: NA · Started 2024-08-01

The goal of this clinical trial is to determine the relative efficacy of fMRI model guided Transcranial Direct Current Stimulation (mgTDCS) in improving the depressive symptoms of patients with Parkin...

Mobile, Alabama, United States
Recruiting
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
NCT04432883 · Phase: NA · Started 2022-10-18

62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to righ...

Albuquerque, New Mexico, United States
Recruiting
Novel Brain Stimulation Treatment for Neuropsychiatric Symptoms in Alzheimer's Disease
NCT06835283 · Phase: NA · Started 2026-08-01

The goal of this pilot study is to test a combination of two non-invasive brain stimulation methods, called iTBS (intermittent theta burst stimulation) and tDCS (transcranial direct current stimulatio...

Houston, Texas, United States
Recruiting
Non-invasive Brain Stimulation to Prepare the Patient for Bariatric Surgery (REBAS)
NCT06874309 · Phase: NA · Started 2024-05-01

Obesity is a chronic metabolic condition characterized by excessive accumulation of body fat, which triggers physiological mechanisms that increase the risk of a wide range of health problems. The mos...

Brno, Czechia, Czechia · Brno, Czechia, Czechia
Recruiting
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
NCT03610763 · Phase: NA · Started 2018-08-15

This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral ...

Louisville, Kentucky, United States · Columbia, Missouri, United States · St Louis, Missouri, United States
Recruiting
Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADH
NCT05354232 · Phase: NA · Started 2022-07-01

The investigators are investigating whether home-based tDCS over the course of four weeks can improve ADHD symptom severity and improve dysexecutive functioning (cognitive control). Further, the inves...

Charlestown, Massachusetts, United States
Recruiting
Trans-cranial Direct Current Stimulation on Alcohol Craving
NCT05854693 · Phase: NA · Started 2023-04-17

The goal of thisclinical trial is to investigate the efficacy of trans cranial direct current stimulation (tDCS) for alcohol craving in individuals with alcohol dependence. The main question it aims t...

Taipei, Taipei CITY, Taiwan
Recruiting
Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety S
NCT07217223 · Phase: NA · Started 2025-09-27

The investigators propose a single-arm, open-label study to evaluate the effectiveness, safety, tolerability and feasibility of at-home transcranial direct current stimulation (tDCS) as a treatment fo...

San Diego, California, United States
Recruiting
tDCS in Post-Acute COVID-19 Patients With SARDs
NCT04890483 · Phase: NA · Started 2021-05-17

Some patients develop "Post-acute COVID-19 syndrome," in which they experience persistent symptoms after recovering from the acute phase of COVID-19 infection. This syndrome may be more significant in...

São Paulo, Brazil
Recruiting
Application of tDCS Stimulation in Controlling Refractory Status Epilepticus
NCT06344338 · Phase: NA · Started 2024-04-01

The purpose of the study is to assess the efficacy and safety of targeting tDCS stimulation for treatment of Refractory status epilepticus...

Beijing, Beijing Municipality, China
Recruiting
Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder
NCT06286930 · Phase: NA · Started 2024-04-24

Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other thera...

Dallas, Texas, United States
Recruiting
tDCS in People With Subthreshold Depression
NCT06517121 · Phase: NA · Started 2026-01-16

This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression....

Hong Kong, Hong Kong
Recruiting
Influence of Physical Exercise on Neuroplasticity and Sensorimotor Networks in Older Adults
NCT07438808 · Phase: NA · Started 2026-02-04

The purpose of this study is to investigate the influence of a single session of moderate aerobic exercise on motor cortex neuroplasticity in older adults, both alone and in combination with transcran...

Loos, Nord, France
Recruiting
tdCS Combined With Treadmill Training in Patients With Multiple Sclerosis
NCT06986278 · Phase: NA · Started 2025-05-26

This clinical trial aims to evaluate the therapeutic effectiveness of transcranial direct current stimulation (tDCS), a non-invasive technique that modulates cortical excitability, in combination with...

Toledo, Toledo, Spain · Toledo, Toledo, Spain
Recruiting
Transcranial Direct Current Stimulation for Depression
NCT06187454 · Phase: NA · Started 2020-09-08

Several studies have shown that tDCS is valuable and safe options to improve depressive symptoms in adult patients . However, regarding the tDCS to treat depression in elderly population, only few stu...

Taipei, Taiwan
Recruiting
Treating Loneliness In The Older Adult With Depression With tDCS
NCT06658795 · Phase: NA · Started 2024-10-29

High loneliness is prevalent among older adults and is a significant risk factor for major depression and low recovery rates in patients. Current interventions for loneliness are limited. Previous res...

Guangzhou, Guangdong, China
Recruiting
HD-tDCS for Adolescent Bipolar Depression Targeting S1
NCT07246044 · Phase: NA · Started 2025-09-16

This randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy and underlying biological mechanisms of HD-tDCS targeting the primary somatosensory cortex in adolescents wi...

Nanjing, Jiangsu, China
Recruiting
Transcranial Direct Current Stimulation for Depression
NCT07500064 · Phase: NA · Started 2026-03-30

Background: Depression is a common mental disorder characterized by persistent low mood and anhedonia. Pharmacological and psychotherapeutic treatments demonstrate only moderate efficacy. Non-invasiv...

Hefei, Anhui, China
Recruiting
Chronic Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies
NCT04678635 · Phase: NA · Started 2020-12-12

Systemic autoimmune myopathies are rheumatic diseases that affect the striatum skeletal muscles. The transcranial direct current stimulation technique has been frequent, for example, in patients with ...

São Paulo, São Paulo, Brazil
Recruiting
Transcranial Direct Current Stimulation and Modulation of Affect and Pain
NCT06989749 · Phase: NA · Started 2023-09-09

This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by ...

Hanover, New Hampshire, United States
Recruiting
Resting-State Functional Connectivity as a Predictor of tDCS Effects in Adolescents With Autism Spectrum Disorder
NCT06878326 · Phase: NA · Started 2025-09-01

Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade. Not only that it is transient with littl...

Hung Hom, Kowloon, Hong Kong
Recruiting
Acute Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies
NCT03749538 · Phase: NA · Started 2018-10-01

Systemic autoimmune myopathies are a heterogeneous group of rheumatic diseases that primarily affect the skeletal muscles. The transcranial direct current stimulation technique has been frequent, for ...

São Paulo, Brazil
Recruiting
Combination of Neurostimulation and Psychotherapy to Stop Worrying
NCT06369532 · Phase: NA · Started 2024-03-06

This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative think...

Ghent, East-Flanders, Belgium
Recruiting
Early Psychosis: Investigating Cognition
NCT07196423 · Phase: NA · Started 2026-02-09

The project aims to explore changes in brain chemistry in individuals who have recently experienced psychosis. Recent research suggests that chemicals in the brain, specifically one called glutamate, ...

Nottingham, Nottinghamshire, United Kingdom
Recruiting
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
NCT05035511 · Phase: NA · Started 2022-01-05

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors. Particularly detrimental are the presence of...

Hung Hom, Kowloon, Hong Kong
Recruiting
tDCS to Decrease Opioid Relapse (UH3)
NCT06432465 · Phase: NA · Started 2024-04-17

Investigators will measure behavioral and brain responses following transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) (anode on right DLPFC, cathode on the l...

Providence, Rhode Island, United States
Recruiting
Relieving Chronic Pain in Older Adults With Transcranial Direct Current Stimulation
NCT05617027 · Phase: NA · Started 2023-10-19

The primary objective of this study is to determine, in a healthcare setting, the effectiveness of actual tDCS in reducing pain compared with placebo tDCS. This is a multicenter randomized controlled ...

Montreal, Quebec, Canada · Québec, Quebec, Canada · Sherbrooke, Quebec, Canada
Recruiting
Effects of TDCS Intervention on Neoadjuvant Chemotherapy in Breast Cancer Patients with Mild to Moderate Depression
NCT06741540 · Phase: NA · Started 2025-01-01

Depression and anxiety are associated with higher incidence of tumors, cancer-specific mortality, and all-cause mortality. Compared with patients with other types of cancer, breast cancer patients of...

Hangzhou, Zhejiang, China
Recruiting
Model-Driven Individualized Transcranial Direct Current Stimulation for the Treatment of Insomnia Disorders
NCT06671457 · Phase: NA · Started 2024-11-10

This study is designed to evaluate the efficacy and to explore the best individualized stimulus paradigm of transcranial Electrical Stimulation for insomnia patients....

Shanghai, Shanghai Municipality, China
Recruiting
Effects of tDCS on Motor Cortex During ACL Recovery
NCT06818201 · Phase: NA · Started 2025-11-28

Anterior Cruciate Ligament (ACL) is a prevalent injury, particularly among young and physically active individuals. The efficacy of transcranial direct current stimulation (tDCS) and exercise-based re...

Valencia, Valencia, Spain
Recruiting
tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment
NCT07112521 · Phase: NA · Started 2025-09-01

The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured ...

Helsinki, Uusimaa, Finland
Recruiting
Targeting Repetitive Behaviors in Autism Spectrum Disorder Via Transcranial Direct Current Stimulation
NCT06645587 · Phase: NA · Started 2024-10-03

Repetitive behaviors (RBs) are a prevalent feature of Autism Spectrum Disorder (ASD). There are two groups of RBs: lower-order (e.g. motor stereotypies) and higher-order RBs (e.g. restricted interests...

Rome, Italy, Italy
Recruiting
Efficacy of Transcranial Direct Current Stimulation (tDCS) in Patients Suffering From Pathological Use of Internet Gamin
NCT04120714 · Phase: NA · Started 2020-01-06

The Internet has grown considerably in the last twenty years, and as a result, cases of excessive iinterney use have emerged. These cases, which have clinical similarities with substance addiction, in...

Dijon, France
Recruiting
Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Functi
NCT06305949 · Phase: NA · Started 2024-04-22

The goal of this clinical trial is to evaluate whether the application of optimized transcranial direct current stimulation is more effective compared to sham stimulation for temporary improvement of ...

Bucheon-si, South Korea
Recruiting
Effect of Neuroplasticity Modulation in tDCS Treatment Response Among Schizophrenia Patients With Auditory Hallucination
NCT04629352 · Phase: NA · Started 2024-04-02

Schizophrenia is a severe neuropsychiatric disorder of the brain and is also one of the top ten disabling diseases. A common symptom of schizophrenia (SCZ) is hearing voices inside one's heads which o...

Bengaluru, Karnataka, India
Recruiting
tDCS and Urge in BFRBs
NCT07019571 · Phase: NA · Started 2025-07-08

The goal of this study is to find out if brain stimulation can help people stop skin-picking or nail-biting. The study wants to answer two main questions: 1. Does brain stimulation reduce the urge to...

Lexington, Kentucky, United States
Recruiting
Preventing Chronification of Phantom Limb Pain Through Mirror Therapy in Conjunction With tDCS
NCT07139483 · Phase: NA · Started 2025-03-25

Background: Most amputees experience phantom limb pain (PLP), for years after amputation. Virtually all PLP research to date has focused on the mechanisms of chronic PLP, ignoring the mechanisms of ch...

Raanana, Israel, Israel · Tel Aviv, Israel, Israel · Tel Aviv, Israel
Recruiting
tDCS Associated With Symptom Provocation in the Management of Patients With Resistant Obsessive Compulsive Disorder
NCT06017713 · Phase: NA · Started 2023-10-17

This is a single-center study about patients with severe resistant OCD. Main assumption is that performing 10 tDCS sessions with the anode positioned at the level of the right orbitofrontal cortex, a...

Poitiers, France
Recruiting
Home tDCS for the Treatment of Major Depression.
NCT07510880 · Phase: NA · Started 2026-04-14

The purpose of this multicentric randomized controlled trial is to compare the effectiveness and safety of home-based tDCS for the treatment of major depression versus tDCS treatment in a healthcare c...

L'Hospitalet de Llobregat, Barcelona, Spain · Mataró, Barcelona, Spain · Sabadell, Barcelona, Spain
Recruiting
Transcranial Direct Current Stimulation for Depression
NCT07042217 · Phase: NA · Started 2025-07-01

This study will test the efficacy of transcranial direct current stimulation (tDCS) combined with mindfulness, remotely-delivered using a telemedicine protocol in 25 adults with unipolar depression....

Woodbridge, New Jersey, United States
Recruiting
Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis
NCT06228573 · Phase: NA · Started 2024-10-20

People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of hea...

Hamilton, Ontario, Canada · London, Ontario, Canada · Sherbrooke, Quebec, Canada
Recruiting
Study of the Effectiveness of VRET Combined With tDCS in the Treatment of PTSD in Ukrainian Veterans and Civilians
NCT06806267 · Phase: NA · Started 2025-04-22

A new method is being tested to assist individuals in Ukraine with Post-Traumatic Stress Disorder (PTSD), including veterans and civilians affected by war. The study is a collaboration among Ukrainian...

Berlin, Germany
Recruiting
Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation
NCT06009523 · Phase: NA · Started 2023-10-26

The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideation...

Faye-l'Abbesse, France · Poitiers, France
Recruiting
Transcranial Direct Current Stimulation on Functionality and Pain in Individuals with Patellar Tendinopathy
NCT06729437 · Phase: NA · Started 2024-07-01

The aim of the present study is to investigate the effectiveness of transcranial direct current stimulation (tDCS) prior to a therapeutic eccentric exercise program on parameters related to pain and f...

Valencia, Valencia, Spain
Recruiting
Clinical Efficacy and Long Term Effects of Transcranial Direct Current Stimulation (tDCS) in Children With Attention Def
NCT04704687 · Phase: PHASE3 · Started 2021-01-08

Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurodevelopmental disorder in childhood. Patients with ADHD present inattention, impulsivity and hyperactivity causing s...

Amiens, France
Recruiting
Efficacy and Safety of Transcranial dIrect Current stiMulation in Multiple System Atrophy-Cerebellar Variant
NCT06821256 · Phase: NA · Started 2023-07-03

This is a double-blind, randomized, sham-controlled clinical trial that aim to verify the safety and the efficacy of anodal transcranial direct current stimulation (tDCS) cerebellar symptoms in Multip...

Salerno, Sa, Italy
Recruiting
At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral Sclerosis
NCT07006571 · Phase: NA · Started 2025-05-19

Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease that causes gradual muscle weakness and loss of muscle mass. It affects all muscles that control movement, speech, swallowing,...

Trieste, Trieste, Italy
Recruiting
Efficacy and Safety of tACS vs tDCS in Schizophrenia
NCT06494124 · Phase: NA · Started 2024-04-03

This clinical trial aims to compare the efficacy and safety of transcranial Alternating current stimulation (tACS) vs. transcranial Direct current stimulation (tDCS) vs. sham stimulation in chronic sc...

Bhubaneswar, Odisha, India
Recruiting
Effects and Mechanisms of Transcranial Direct Current Stimulation Combined With Dialectical Behavior Therapy Skills Trai
NCT07565402 · Phase: NA · Started 2026-04-01

Effects and Mechanisms of Transcranial Direct Current Stimulation Combined with Dialectical Behavior Therapy Skills Training in Adults with Attention-Deficit/Hyperactivity Disorder Abstract Adult att...

Nanjing, Jiangsu, China
Recruiting
tDCS for Catatonic Depression in Down Syndrome: A Pilot Study
NCT06866925 · Phase: NA · Started 2025-09-12

This study evaluates the efficacy of transcranial direct current stimulation (tDCS) for depression with catatonia in individuals with Down syndrome (DS). 62 patients will be randomized to receive 15 s...

Lyon, Auvergne-Rhône-Alpes, France
Recruiting
tDCS for Laryngeal Dystonia
NCT06830174 · Phase: NA · Started 2025-04-14

This project will apply transcranial direct current stimulation (tDCS) to multiple brain areas to evaluate the effects as a potential treatment for laryngeal dystonia (formerly spasmodic dysphonia)....

New Haven, Connecticut, United States
Recruiting
Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
NCT06834217 · Phase: NA · Started 2025-09-12

Obsessive-compulsive disorder (OCD) is associated with substantial impairments in quality of life and is among the most disabling psychiatric disorders. Exposure therapy is among the first-line of tre...

New Haven, Connecticut, United States
Recruiting
Efficacy of Home-delivered Transcranial Direct Electrical Stimulation or Chronic Pain
NCT07211256 · Phase: NA · Started 2025-01-09

This clinical investigation aims to evaluate the efficacy and safety of a home-based device providing electrical stimulation of the brain named transcranial direct current stimulation (tDCS ) , in pat...

Boulogne-Billancourt, Hauts de Seine, France
Recruiting
Cumulative and Booster Effects of Multisession Prefrontal tDCS in ASD Adolescents
NCT06272669 · Phase: NA · Started 2022-06-02

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behavior. To date, ASD has no known cure, and the disor...

Hung Hom, Kowloon, Hong Kong
Recruiting
Transcranial Direct Current Stimulation in Children With Autism
NCT07092280 · Phase: NA · Started 2026-04-01

Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a signific...

Staten Island, New York, United States
Recruiting
RCT of At-Home tDCS for Depression in Pregnancy
NCT05097586 · Phase: NA · Started 2021-11-08

This is a randomized, sham-controlled trial to determine whether treatment with transcranial direct current stimulation (tDCS) is superior to a sham condition at reducing the symptoms of depression in...

Toronto, Ontario, Canada · Toronto, Ontario, Canada
Recruiting
Effect of Transcranial Direct Current Stimulation on Postoperative Delirium in Elderly Patients
NCT06678529 · Phase: NA · Started 2024-11-01

To evaluate the efficacy of transcranial direct current stimulation (tDCS) in reducing the incidence of postoperative delirium (POD) in elderly patients undergoing hip fracture surgery. This single-c...

Taiyuan, Shanxi, China
Recruiting
Transcranial Direct Current Stimulation for Post-stroke Fatigue
NCT05816603 · Phase: PHASE2 · Started 2023-05-23

The investigators hypothesize that delivery of anodal tDCS to the left frontal head region will reduce fatigue severity following stroke....

New York, New York, United States
Recruiting
Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation
NCT05958381 · Phase: NA · Started 2023-10-18

The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought ...

Richardson, Texas, United States
Recruiting
Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophys
NCT06495684 · Phase: NA · Started 2024-03-12

The purpose of this clinical trial is to investigate the effects of multiple sessions of transcranial direct current stimulation (tDCS) delivered while participants complete tasks that target social l...

Albuquerque, New Mexico, United States
Recruiting
Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum P
NCT05691283 · Phase: NA · Started 2023-06-20

The purpose of this research study is to investigate the effects of transcranial direct current stimulation (tDCS) on some of the challenges faced by children with Autism Spectrum Disorder (ASD)....

Dalls, Texas, United States
Recruiting
Transcranial Direct Current Stimulation in Children With Autism Spectrum Disorder
NCT06880159 · Phase: NA · Started 2025-09-01

Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade. Not only that it is transient with littl...

Hung Hom, Kowloon, Hong Kong
Recruiting
Modification of Inhibitory Control and Craving Through Transcranial Direct Current Stimulation (tDCS) as an Add-On Treat
NCT06959342 · Phase: NA · Started 2024-09-23

The aim of this project is to investigate the potential of transcranial direct current stimulation (tDCS) to reduce cognitive deficits and substance craving in individuals with substance use disorders...

Mannheim, Germany · Wiesloch, Germany
Recruiting
Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop
NCT07592221 · Phase: NA · Started 2026-06-01

This study aims to determine if combining the treatments of transcranial direct current stimulation (tDCS) and functional electrical stimulation (FES) will better help persons with stroke who have dif...

Philadelphia, Pennsylvania, United States
Recruiting
Cumulative and Booster Effects of Multisession Prefrontal Transcranial Direct Current Stimulation in Adolescents With AS
NCT05492032 · Phase: NA · Started 2022-06-02

Autism spectrum disorder (ASD) is a pervasive and lifelong developmental disorder that currently affects 1 in 54 children. Individuals with autism are often severely impaired in communication, social ...

Hung Hom, Kowloon, Hong Kong
Recruiting
Understanding the Neural Mechanisms Behind tDCS
NCT04577677 · Phase: NA · Started 2020-09-01

The aim of the study is to investigate the neural mechanisms underpinning transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique in which a direct current is passed t...

Leuven, Vlaams-Brabant, Belgium
Recruiting
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Corti
NCT07191327 · Phase: NA · Started 2026-01-28

This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (P...

Ann Arbor, Michigan, United States
Recruiting
Home-based Transcranial Direct Current Stimulation (tDCS) Compared to Duloxetine: Non-inferiority Clinical Trial (FIBROS
NCT07203339 · Phase: NA · Started 2025-09-30

Fibromyalgia is characterized by widespread pain, fatigue, non-restorative sleep, and psychocognitive alterations, compromising quality of life and leading to absenteeism and early retirement. Up to 7...

Porto Alegre, Rio Grande do Sul, Brazil
Recruiting
Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia
NCT04084795 · Phase: NA · Started 2025-01-21

Fibromyalgia (FM) is a generalized, widespread chronic pain disorder and has an estimated prevalence of 2%-4% in the general population. Current pharmacological and psychological interventions frequen...

Barcelona, Catalonia, Spain
Recruiting
The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities
NCT04732052 · Phase: NA · Started 2022-09-01

Aggressive behaviours are highly prevalent among people with developmental disabilities, both in community and inpatient or residential settings, with adverse consequences for the individuals involved...

Kingston, Ontario, Canada
Recruiting
Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
NCT04477330 · Phase: NA · Started 2020-09-01

Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using b...

Chicago, Illinois, United States
Recruiting
Using tDCS in Speech-based Stroke Rehabilitation
NCT03452202 · Phase: NA · Started 2019-01-11

The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation...

New York, New York, United States · White Plains, New York, United States
Recruiting
TDCS Stimulation After Covid-19 Infection
NCT06183424 · Phase: NA · Started 2023-10-01

In this study, the effects of bilateral stimulation of the dorsolateral prefrontal cortex (DLPFC) with active tDCS (transcranial direct stimulation/transcranial direct stimulation) on neurocognitive (...

Antalya, Turkey (Türkiye)
Recruiting
Efficacy of Dorso-lateral Prefrontal Cortex Stimulation by tDCS in Motor Conversion Disorder Patients
NCT04097184 · Phase: NA · Started 2021-03-05

Conversion disorder refers to impaired voluntary motor or sensory functions that are not compatible with a well-known neurological condition. This disorder affects up to 30% of hospitalized patients i...

Nîmes, Gard, France · Montpellier, Hérault, France · Montpellier, Hérault, France
Recruiting
Cortical Stimulation by Direct Current for the Treatment of Chronic Pain : Pilot-study of a Stimulation Device at Home
NCT02346396 · Phase: NA · Started 2015-02-09

The purpose of this study is to confirm the analgesic effect of tDCS in neuropathic chronic pain, to estimate the importance and the duration of this effect, and to improve its efficiency by the use a...

Bron, France
Recruiting
Unilateral M1 Anodal tDCS to Enhance Learning in a Gross Movement Videogame Task
NCT07447882 · Phase: NA · Started 2025-04-23

Virtual reality as a gaming method is being used more regularly due to its immersive environments and total body playability. A few studies have used VR paired with brain stimulation as a clinical tre...

Indianapolis, Indiana, United States
Recruiting
Examining tDCS Effect on Cannabis Use Disorder in Patients With Schizophrenia
NCT04871048 · Phase: NA · Started 2023-02-15

Cannabis use disorder is a frequent comorbidity of schizophrenia, associated with increased symptoms and less adherence to therapy. Validated care has limited effectiveness in this population and deve...

Bron, France · Clermont-Ferrand, France · Clermont-Ferrand, France
Recruiting
Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD
NCT07153692 · Phase: NA · Started 2025-07-17

This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism. Subjects are randomly split into two groups: control ...

Hangzhou, Zhejiang, China
Recruiting
CIFASD 5 tDCS and Cognitive Training
NCT05456321 · Phase: NA · Started 2022-11-10

This is a randomized placebo-controlled trial of cognitive training with transcranial direct current stimulation (tDCS) for children and adolescents (ages 8 - 17 years) with prenatal alcohol exposure ...

Minneapolis, Minnesota, United States
Recruiting
Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheime
NCT05509387 · Phase: NA · Started 2022-09-01

There is currently little symptomatic therapy for Alzheimer's Disease (AD) and nothing effective for individuals with Frontotemporal dementia (FTD). However, neuromodulation with transcranial direct c...

Toronto, Ontario, Canada
Recruiting
Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder
NCT07158853 · Phase: NA · Started 2026-02-04

The overall goal of this study is to investigate the added benefit of a neuromodulation intervention in individuals under buprenorphine maintenance treatment for OUD (bOUD)....

Minneapolis, Minnesota, United States
Recruiting
Effectiveness of tDCS on Reducing Craving in Patients Practicing Chemsex: a Single-center, Double-blind, Randomized Cont
NCT05945199 · Phase: NA · Started 2024-07-29

The aim of this research is to evaluate the efficacy of a new treatment for chemsex or "chemical sex", the use of psychoactive substances to modify sexual experience and performance. This treatment, c...

Dijon, France
Recruiting
Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatme
NCT05188183 · Phase: NA · Started 2022-09-01

The investigators have designed a pragmatic trial of home-based transcranial direct current stimulation (tDCS) for phantom limb pain (PLP), the PLP-EVEREST trial (PLP-EffectiVEness pRagmatic Stimulati...

Cambridge, Massachusetts, United States
Recruiting
Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms
NCT07246993 · Phase: NA · Started 2026-03-05

This project investigates an innovative combination of non-invasive neuromodulation (transcranial direct current stimulation - tDCS) and cognitive training as a novel treatment approach aimed at impro...

Minneapolis, Minnesota, United States
Recruiting
Machine-Learning Based EEG Biomarkers for Personalized Interventions
NCT06531317 · Phase: Not specified · Started 2023-10-05

The goal of this observational study is to develop a machine learning model to predict the outcome of a transcranial direct current stimulation (tDCS) treatment in patients suffering from neuropathic ...

Badalona, Barcelona, Spain
Recruiting
Prismatic Lenses and tDCS in Neglect
NCT05842551 · Phase: NA · Started 2023-03-07

The goal of this study is to to evaluate the effect and feasibility of a rehabilitation protocol with prismatic lenses associated with tDCS, compared to a prismatic lens rehabilitation protocol associ...

Bari, Ba, Italy
Recruiting
Impact of Anodal tDCS and Virtual Reality on Cognitive Dysfunction in Patients With Multiple Sclerosis
NCT07114809 · Phase: NA · Started 2024-09-02

Cognitive impairment (CI) affects a large amount of patients with Multiple Sclerosis (PwMS) even in the early stages of the disease, increasing the perception of fatigue and compromising the quality o...

Genova, Italy, Italy · Genova, Italy, Italy · Genova, Italy, Italy
Recruiting
Dual-task Training Combined With tDCS on Cognitive-motor Performance and Brain Activity in Stroke Patients
NCT06769672 · Phase: NA · Started 2025-01-01

The purpose of this study is to evaluate tDCS combined with cognitive-motor training on dual-task interference during dual-task walking, dual-task foot pedaling and the corresponding alterations of br...

Hong Kong, Hong Kong
Recruiting
Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands
NCT04885322 · Phase: NA · Started 2021-04-14

The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are modulated b...

Sacramento, California, United States
Recruiting
Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa
NCT07141979 · Phase: NA · Started 2025-11-01

Orthorexia Nervosa (ON); is a condition characterized by individuals being overly focused on healthy eating habits, constantly checking and classifying the foods they will consume. ON has not yet been...

Istanbul, Turkey (Türkiye)
Recruiting
Does tDCS Change Synaptic Density in the Brains of Patients With Schizophrenia
NCT05435300 · Phase: Not specified · Started 2021-09-17

This study will examine changes in synaptic density with transcranial direct current stimulation (tDCS) in the brains of patients with schizophrenia. Synaptic density levels will be measured using a n...

Toronto, Ontario, Canada
Recruiting
TDCS to Improve Post-Stroke Cognitive Impairment
NCT05195398 · Phase: NA · Started 2022-09-01

The investigators will conduct a randomized, double-blinded, sham-controlled trial of approximately 60 patients with minor stroke and post-stroke mild cognitive impairment (psMCI). Participants will b...

Baltimore, Maryland, United States
Recruiting
A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931
NCT05730023 · Phase: NA · Started 2023-02-01

Primary Progressive Aphasia (PPA) is a syndrome due to different neurodegenerative disorders selectively disrupting language functions. PPA specialist care is underdeveloped. There are very few specia...

Brescia, BS, Italy · Milan, MI, Italy · Milan, MI, Italy
Recruiting
Tdcs And cogNitive traininG cOmbined for AUD (TANGO)
NCT05062369 · Phase: NA · Started 2022-03-03

The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches us...

Minneapolis, Minnesota, United States
Recruiting
Cerebellar tDCS in Children With Autism Spectrum Disorder
NCT04446442 · Phase: NA · Started 2019-06-04

The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorde...

Dallas, Texas, United States · Dallas, Texas, United States
Recruiting